Minichromosome Maintenance Complex Component 3 (MCM3) Peptid
Kurzübersicht für Minichromosome Maintenance Complex Component 3 (MCM3) Peptid (ABIN936013)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTRQPDAK
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MCM3 antibody,
Alternative Names: MCM3 control peptide, MCM3 antibody Blocking Peptide, Anti-MCM3 Blocking Peptide, Minichromosome Maintenance Complex Component 3 Blocking Peptide, HCC5 Blocking Peptide, MGC1157 Blocking Peptide, P1-MCM3 Blocking Peptide, P1.h Blocking Peptide, RLFB Blocking Peptide, MCM3, MCM-3, MCM 3, MCM-3 Blocking Peptide, MCM 3 Blocking Peptide -
Aufreinigung
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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Hintergrund
- MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
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Molekulargewicht
- 91 kDa
Target
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