Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptid
KCTD17
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle KCTD17 Produkte
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- DQAEFLCVVS KELHSTPNGL SSESSRKTKS TEEQLEEQQQ QEEEVEEVEV
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- KCTD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
- Hintergrund
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Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. May be involved in endoplasmic reticulum calcium ion homeostasis.
Protein Size: 321 - Gen-ID
- 79734
- NCBI Accession
- NM_001282684, NP_001269613
- UniProt
- Q8N5Z5
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