Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptid
Kurzübersicht für Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptid (ABIN5672784)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Sequenz
- SKELHSTPNG LSSESSRKTK STEEQLEEQQ QQEEEVEEVE VEQVQVEADA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- KCTD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
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Hintergrund
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Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. May be involved in endoplasmic reticulum calcium ion homeostasis.
Protein Size: 321 -
Gen-ID
- 79734
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NCBI Accession
- NM_001282684, NP_001269613
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UniProt
- Q8N5Z5
Target
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