Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptid
CDKN1C
Reaktivität: Human
Wirt: Synthetic
WB
Produktnummer ABIN5518457
Kurzübersicht für Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptid (ABIN5518457)
Target
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- SACRSLFGPV DHEELSRELQ ARLAELNAED QNRWDYDFQQ DMPLRGPGRL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Hintergrund
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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2,
Protein Size: 316 -
Gen-ID
- 1028
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NCBI Accession
- NM_000076, NP_000067
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UniProt
- P49918
Target
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