Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptid
CDKN1C
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CDKN1C Produkte
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- LNAEDQNRWD YDFQQDMPLR GPGRLQWTEV DSDSVPAFYR ETVQVGRCRL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CDKN1C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Synonyme
- BWCR Peptide, BWS Peptide, KIP2 Peptide, WBS Peptide, p57 Peptide, p57Kip2 Peptide, cb961 Peptide, p27Xic1-a Peptide, zgc:86618 Peptide, AL024410 Peptide, CDKI Peptide, Kip2 Peptide, p57(kip2) Peptide, p57KIP2 Peptide, cyclin dependent kinase inhibitor 1C Peptide, cyclin-dependent kinase inhibitor 1Ca Peptide, cyclin-dependent kinase inhibitor 1C (P57) Peptide, cyclin-dependent kinase inhibitor 1C Peptide, CDKN1C Peptide, cdkn1ca Peptide, Cdkn1c Peptide
- Hintergrund
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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2
Protein Size: 305 - Gen-ID
- 1028
- NCBI Accession
- NM_000076, NP_000067
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