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Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptid

RRM2B Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511518
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 21 Werktagen

Kurzübersicht für Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptid (ABIN5511518)

Target

RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

    Hintergrund

    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

    Protein Size: 299

    Gen-ID

    50484
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