Tumor Protein P53 (TP53) (C-Term) Peptid
TP53
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle p53 (TP53) Produkte
- p53 (TP53) (Tumor Protein P53 (TP53))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- LNEALELKDA QAGKEPGGSR AHSSHLKSKK GQSTSRHKKL MFKTEGPDSD
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-P53 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Hintergrund
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This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons.
Alias Symbols: TP53,P53,
Protein Size: 393 - Gen-ID
- 7157
- UniProt
- P04637
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