Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptid
U2AF1L4
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN2185358
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptid (ABIN2185358)
Target
Splicing factor U2AF 26 kDa subunit (U2AF1L4)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-U2AF1L4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Splicing factor U2AF 26 kDa subunit (U2AF1L4) peptide
U2AF1L4 Reaktivität: Human, Hund, Maus, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
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Hintergrund
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U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Size: 220 -
Molekulargewicht
- 24 kDa
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Gen-ID
- 199746
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UniProt
- Q8WU68
Target
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