Charged Multivesicular Body Protein 5 (CHMP5) (C-Term) Peptid
CHMP5
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
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- Target Alle CHMP5 Produkte
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- Protein Region
- C-Term
- Spezies
- Human, Maus
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- Synthetic peptide located within the following region: < a href='http://www.ncbi.nlm.nih.gov/blast/Blast.cgi?PROGRAM=blastp&CLIENT=web&SERVICE=plain&PAGE=Proteins&CMD=Put&DATABASE=nr&CDD_SEARCH=1&AUTO_FORMAT=Semi-auto&SHOW_OVERVIEW=on&SHOW_LINKOUT=on&GET_SEQUENCE=on&NCBI_GI=on&ALIGNMENTS =50&I_THRESH=0.005&QUERY=
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Chmp5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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Charged Multivesicular Body Protein 5 (CHMP5) peptide
CHMP5 Reaktivität: Human, Maus, Rind (Kuh), Ratte Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- Synonyme
- SNF7DC2 Peptide, cgi-34 Peptide, hspc177 Peptide, pnas-2 Peptide, vps60 Peptide, chmp5 Peptide, zgc:64125 Peptide, C9orf83 Peptide, HSPC177 Peptide, PNAS-2 Peptide, Vps60 Peptide, 2210412K09Rik Peptide, AW545668 Peptide, RGD1305968 Peptide, charged multivesicular body protein 5 S homeolog Peptide, charged multivesicular body protein 5b Peptide, charged multivesicular body protein 5 Peptide, charged multivesicular body protein 5 L homeolog Peptide, chromatin modifying protein 5 Peptide, chmp5.S Peptide, chmp5b Peptide, CHMP5 Peptide, chmp5.L Peptide, chmp5 Peptide, Chmp5 Peptide
- Hintergrund
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Chmp5 is a probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Alias Symbols: 2210412K09Rik, AW545668
Protein Size: 219 - Molekulargewicht
- 24 kDa
- Gen-ID
- 76959
- NCBI Accession
- NM_029814, NP_084090
- UniProt
- Q9D7S9
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