CAMP Responsive Element Modulator (CREM) (C-Term) Peptid
CREM
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, WB
Produktnummer ABIN1540899
Kurzübersicht für CAMP Responsive Element Modulator (CREM) (C-Term) Peptid (ABIN1540899)
Target
CREM
(CAMP Responsive Element Modulator (CREM))
Spezies
Human, Ratte
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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CAMP Responsive Element Modulator (CREM) peptide
CREM Reaktivität: Human, Ratte, Rind (Kuh), Maus Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CREM (CAMP Responsive Element Modulator (CREM))
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Hintergrund
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Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Size: 357 -
Molekulargewicht
- 39 kDa
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Gen-ID
- 25620
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NCBI Accession
- NM_001110860, NP_001104330
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UniProt
- Q03061
Target
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