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anti-Rat (Rattus) CDX2 Antikörper:
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Human Monoclonal CDX2 Primary Antibody für BI, WB - ABIN967663
Hinoi, Loda, Fearon: Silencing of CDX2 expression in colon cancer via a dominant repression pathway. in The Journal of biological chemistry 2003
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Human Polyclonal CDX2 Primary Antibody für IHC (p), IP - ABIN151575
Verzi, Hatzis, Sulahian, Philips, Schuijers, Shin, Freed, Lynch, Dang, Brown, Clevers, Liu, Shivdasani: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 5 Pubmed References
Human Monoclonal CDX2 Primary Antibody für ELISA, WB - ABIN1724918
Lee, Vogt, Hsiao, Osunkoya: CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules. in Tumour biology 2012
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Human Monoclonal CDX2 Primary Antibody für FACS, ELISA - ABIN1724921
Liu, Zhang, Zhan, Brock, Herman, Guo: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. in Cancer biology & therapy 2012
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Human Polyclonal CDX2 Primary Antibody für ELISA, WB - ABIN251330
Qualtrough, Hinoi, Fearon, Paraskeva: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. in Gut 2002
Human Monoclonal CDX2 Primary Antibody für IHC (p), IHC - ABIN152122
Flisikowska, Merkl, Landmann, Eser, Rezaei, Cui, Kurome, Zakhartchenko, Kessler, Wieland, Rottmann, Schmid, Schneider, Kind, Wolf, Saur, Schnieke: A porcine model of familial adenomatous polyposis. in Gastroenterology 2012
Cow (Bovine) Polyclonal CDX2 Primary Antibody für WB - ABIN2777319
Saad, Cho, Silverman, Liu: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. in American journal of clinical pathology 2004
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Human Monoclonal CDX2 Primary Antibody für ELISA, WB - ABIN560320
Zulueta, Caretti, Signorelli, Dallolio, Trinchera: Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.
Data show that a two-marker panel of p40 (zeige IL9 Antikörper) (DeltaNp63) and CDX2 is highly sensitive and specific.
our findings demonstrated that MDR1 (zeige TBC1D9 Antikörper) expression is regulated by CDX2 and is related to drug resistance in ovarian mucinous adenocarcinoma.
The data presented provide a novel insight into how CDX2 is implicated in the transcriptional regulation of LAMC2 (zeige LAMC2 Antikörper) in intestinal epithelial cells, a function that is impaired during mucosal inflammation where a high level of TNF-alpha (zeige TNF Antikörper) is present.
Cytapheresis might induce CDX2 expression without affecting the cell proliferation, thus resulting in mucosal healing with goblet cell restoration.
SOX2 (zeige SOX2 Antikörper) expression induces a cellular stem cell state in human colorectal cancer (CRC (zeige CALR Antikörper)) with a decreased expression of CDX2. Furthermore, a down-regulated expression of CDX2 results in a poor patient prognosis in CRC (zeige CALR Antikörper).
A small subset (5%) of hepatocellular carcinomas are CDX2 positive.
A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (zeige HNF4A Antikörper) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (zeige HNF4A Antikörper) in human biopsy samples.
Colon cancer cells expressing CDX2 are less deformable, a feature that has been shown to correlate with poor metastatic potential.
Results show that CDX2 and Fbw7 (zeige FBXW7 Antikörper) expression is inversely correlated during colon cell differentiation and that CDX2 expression is regulated by Fbw7 (zeige FBXW7 Antikörper) in a GSK3b (zeige GSK3b Antikörper)-dependent manner.
Aberrant DNA methylation (zeige HELLS Antikörper) of SOX2 (zeige SOX2 Antikörper) and CDX2 genes contributes to the development of IM. Notably, SOX2 (zeige SOX2 Antikörper) may play a role in establishing and maintaining the methylation status of the CDX2 gene in gastric tissues and cells.
Data show that SLC7A7 (zeige Slc7a7 Antikörper) is a CDX2 target gene, and that CDX2 binds directly to the SLC7A7 (zeige Slc7a7 Antikörper) promoter.
these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.
showed novel molecular regulation of CDX2 on Oct4 (zeige POU5F1 Antikörper), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (zeige POU5F1 Antikörper) in embryo of mammals other than mouse
including Wnt (zeige WNT2 Antikörper) and Fgf pathway components active in the axial progenitor niche. Our data demonstrate that integration of the Cdx (zeige CDX1 Antikörper)/Hox (zeige MSH2 Antikörper) and T Brachyury (zeige TBX1 Antikörper) transcriptional networks controls differential axial growth during vertebrate trunk elongation
Cdx (zeige CDX1 Antikörper) members interact with the SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper) complex and make direct contact with Brg1 (zeige SMARCA4 Antikörper), a catalytic member of SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper). Both Cdx2 and Brg1 (zeige SMARCA4 Antikörper) co-occupy a number of Cdx (zeige CDX1 Antikörper) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (zeige SMARCA4 Antikörper) occupancy occurs coincident with chromatin remodeling at some of these loci.
The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (zeige MSH2 Antikörper) gene.
Cdx1 (zeige CDX1 Antikörper)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (zeige ADCY10 Antikörper) and a block in hematopoietic differentiation from yolk sac (zeige ADCY10 Antikörper)-derived cells in culture.
this study shows that Aloe vera (zeige IGF2BP3 Antikörper) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer
Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (zeige HOXB7 Antikörper) and Cdx2 in colon cancer cells.
CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (zeige NFS1 Antikörper) may be activated or repressed.
cells in preimplantation embryos that localized in an initial outer position initiated the expression of Cdx2. cells that changed their position from an outer to an inner position downregulated Cdx2 expression and contributed to the inner cell mass.
findings illuminated a role for NOD1 (zeige NOD1 Antikörper) signaling in attenuating H. pylori-induced Cdx2 expression in gastric epithelial cells
results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
caudal type homeobox 2
, caudal type homeobox transcription factor 2
, caudal type homeo box transcription factor 2
, homeobox protein CDX-2
, caudal-type homeobox protein 2
, caudal type homeo box 2
, caudal-type homeobox transcription factor 2