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Rekombinanter CDX2 Antikörper (AA 150-249)

CDX2 Reaktivität: Human ELISA, Coat, IHC (f) Wirt: Kaninchen Monoclonal CDX2-2951R unconjugated Recombinant Antibody
Produktnummer ABIN6939060
  • Target Alle CDX2 Antikörper anzeigen
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 21
    • 18
    • 12
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-249
    Reaktivität
    • 131
    • 47
    • 42
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 88
    • 40
    • 3
    Kaninchen
    Klonalität
    • 84
    • 46
    Monoklonal
    Konjugat
    • 81
    • 10
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDX2 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 71
    • 30
    • 30
    • 20
    • 19
    • 15
    • 14
    • 13
    • 12
    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
    Kreuzreaktivität (Details)
    Human,
    Aufreinigung
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    Immunogen
    Recombinant fragment (around aa150-249) of human CDX2 protein (exact sequence is proprietary)
    Klon
    CDX2-2951R
    Isotyp
    IgG
    Top Product
    Discover our top product CDX2 Primärantikörper
  • Applikationshinweise

    Positive Control: HT29 cells. Colon Carcinoma.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Haltbarkeit
    24 months
  • Target
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    Andere Bezeichnung
    CDX2 (CDX2 Produkte)
    Synonyme
    CDX2 antikoerper, MGC130987 antikoerper, cdx3-like antikoerper, CDX-3 antikoerper, CDX3 antikoerper, CDX-2 antikoerper, Cdx-2 antikoerper, caudal type homeobox 2 antikoerper, caudal type homeobox 2 L homeolog antikoerper, caudal type homeo box 2 antikoerper, CDX2 antikoerper, cdx2.L antikoerper, Cdx2 antikoerper
    Hintergrund
    Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2,CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)
    Cellular localisation: Nuclear
    Molekulargewicht
    40kDa
    Gen-ID
    1045, 174249
    UniProt
    Q99626
    Pathways
    Peptide Hormone Metabolism, Stem Cell Maintenance
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