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PD-1 Proteine

(Programmed Cell Death 1 (PDCD1))

May have a role in the regulation of spermatogenesis..

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PD-1 Protein (AA 25-167) (Fc Tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Immobilized Human PD-1, hFc Tag at 1 μg/mL (100 µL/Well).

6 Abbildungen

Produktnummer ABIN7275419

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PD-1 Protein (AA 25-167) (His tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

6 Abbildungen

Produktnummer ABIN7275418

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PD-1 Protein (AA 25-167) (mFc Tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Immobilized Human PD-1, mFc Tag at 1 μg/mL (100 μL/well) on the plate.

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Produktnummer ABIN7275420

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PD-1 Protein (AA 21-167) (Fc Tag)

PDCD1 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Immobilized Cynomolgus PD-1, hFc Tag at 0.

4 Abbildungen

Produktnummer ABIN7275417

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PD-1 Protein (AA 25-167) (Fc-Avi Tag,Biotin)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Immobilized Human PD-L1, mFc tag at 2 μg/mL (100 μL/Well).

4 Abbildungen

Produktnummer ABIN7275422

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PD-1 Protein (AA 25-167) (His-Avi Tag,Biotin)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Immobilized Biotinylated Human PD-1, His Tag at 0.

4 Abbildungen

Produktnummer ABIN7275421

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PD-1 Protein (AA 25-167) (Fc-His Tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ELISA

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Produktnummer ABIN6961149

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PD-1 Protein (AA 24-170) (mFc-His Tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA

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Produktnummer ABIN6961098

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PD-1 Protein (AA 25-167) (Fc Tag)

PDCD1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Mouse PD-1 on Tris-Bis PAGE under reduced condition.

SDS

Mouse PD-L1, His Tag captured on CM5 Chip via Anti-His Antibody can bind Mouse PD-1 , hFc Tag with an affinity constant of 0.

SPR

SEC-HPLC

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Produktnummer ABIN7275423

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PD-1 Protein (AA 25-167) (Fc Tag,Biotin)

PDCD1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Biotinylated Mouse PD-1 on Tris-Bis PAGE under reduced condition.

SDS

Mouse PD-L1, hFc Tag immobilized on CM5 Chip can bind Biotinylated Mouse PD-1, hFc Tag with an affinity constant of 1.

SPR

SEC-HPLC

3 Abbildungen

Produktnummer ABIN7275424

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PD-1 Protein (AA 25-167) (His tag)

HPLC verified PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Immobilized Human PD-1, His Tag (ABIN2181606,ABIN2181605) at 2 μg/mL (100 μL/well) can bind Nivolumab with a linear range of 0.

ELISA

Human PD-1, His Tag (HPLC-verified) on SDS-PAGE under reducing (R) condition.

SDS

Immobilized Human PD-1, His Tag with a linear range of 0.

Bind

3 Abbildungen

4 Referenzen

Produktnummer ABIN2181605

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PD-1 Protein (AA 25-167) (Fc Tag)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Human PD-1, Fc Tag (HPLC-verified) on SDS-PAGE under reducing (R) condition.

SDS

Immobilized Human PD-L1, His Tag with a linear range of 0.

Bind

Immobilized Human PD-L2, His Tag with a linear range of 0.

Bind

3 Abbildungen

6 Referenzen

Produktnummer ABIN2181607

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PD-1 Protein (AA 1-110) (GST tag)

PDCD1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Programmed Cell Death 1 (PDCD1) (AA 1-110) protein (GST tag) (ABIN1314407)

1 image

1 reference

Produktnummer ABIN1314407

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PD-1 Protein (AA 22-170) (His-DYKDDDDK-Strep II Tag)

PDCD1 Spezies: Human Wirt: HEK-293T Cells Recombinant WB, SDS, ELISA, PI

Image no. 2 for Programmed Cell Death 1 (PDCD1) (AA 22-170) protein (His-DYKDDDDK-Strep II Tag) (ABIN1314404)

Image no. 1 for Programmed Cell Death 1 (PDCD1) (AA 22-170) protein (His-DYKDDDDK-Strep II Tag) (ABIN1314404)

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Produktnummer ABIN1314404

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PD-1 Protein (AA 33-145) (His-DYKDDDDK-Strep II Tag)

PDCD1 Spezies: Human Wirt: HEK-293T Cells Recombinant WB, SDS, ELISA, PI

Image no. 2 for Programmed Cell Death 1 (PDCD1) (AA 33-145) protein (His-DYKDDDDK-Strep II Tag) (ABIN1314403)

Image no. 1 for Programmed Cell Death 1 (PDCD1) (AA 33-145) protein (His-DYKDDDDK-Strep II Tag) (ABIN1314403)

2 Abbildungen

Produktnummer ABIN1314403

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PD-1 Protein (AA 25-167) (Fc Tag)

PDCD1 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active

Immobilized Cynomolgus PD-1, Fc Tag (ABIN2181604,ABIN2181603) at 2 μg/mL (100 μL/well) can bind Nivolumab with a linear range of 0.

ELISA

Cynomolgus PD-1, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions.

SDS

Immobilized Human PD-L1, Mouse IgG1 Fc Tag, low endotoxin (Hied) (ABIN2870682,ABIN2870683) at 5 μg/mL (100 μL/well) can bind Cynomolgus PD-1, Fc Tag (ABIN2181604,ABIN2181603) with a linear range of 3-33 ng/mL (QC tested).

ELISA

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Produktnummer ABIN2181603

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PD-1 Protein (AA 25-167) (His tag)

PDCD1 Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active

Immobilized Rhesus macaque PD-1, His Tag (ABIN6992382) at 2 μg/mL (100 μL/well) can bind nivolumab with a linear range of 0.

ELISA

Rhesus macaque PD-1, His Tag on under reducing (R) condition.

SDS

Immobilized Biotinylated Human PD-L2, Fc,Avitag (ABIN2870562,ABIN2870563) at 1 μg/mL (100 μL/well) on streptavidin precoated (0.

ELISA

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Produktnummer ABIN6992382

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PD-1 Protein (AA 25-167) (Fc Tag)

PDCD1 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Mouse PD-1, Fc Tag on SDS-PAGE under reducing (R) condition.

SDS

Bind

2 Abbildungen

1 reference

Produktnummer ABIN2181617

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PD-1 Protein (AA 25-167) (His tag,AVI tag,Biotin)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Biotinylated Human PD-1 (recommended for biopanning) on SDS-PAGE under reducing (R) condition.

SDS

Bind

2 Abbildungen

4 Referenzen

Produktnummer ABIN2181593

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PD-1 Protein (AA 25-167) (His tag,Fc Tag,AVI tag,Biotin)

PDCD1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Immobilized Human PD-L2, Fc Tag (HPLC verified) (ABIN2181601,ABIN2749238) at 5 μg/mL (100 μL/well) can bind Biotinylated Human PD-1, Fc,Avitag,His Tag (ABIN6973192) with a linear range of 10-40 ng/mL (Routinely tested).

ELISA

Biotinylated Human PD-1, Fc,Avitag,His Tag on under reducing (R) and ing (NR) conditions.

SDS

Immobilized Human PD-L1, Fc Tag (Hied) (ABIN2181596,ABIN2181595) at 5 μg/mL (100 μL/well) can bind Biotinylated Human PD-1, Fc,Avitag,His Tag (ABIN6973192) with a linear range of 10-156 ng/mL (QC tested).

ELISA

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Produktnummer ABIN6973192

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Weitere Treffer anzeigen

Aktuelle Publikationen für unsere PD-1 Proteine

Assi, Wong, Tipton, Mei, Wong, Razo, Chan, Howng, Sagert, Krimm, Diep, Jang, Nguyen, Lapuyade, Singson, Villanueva, Paidhungat, Liu, Rangan, Vasiljeva, West, Richardson, Irving, Daniel, Belvin et al.: "Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents. ..." in: Cancer immunology research, Vol. 9, Issue 12, pp. 1451-1464, (2022) (PubMed).

Curnock, Bossi, Kumaran, Bawden, Figueiredo, Tawar, Wiseman, Henderson, Hoong, Gonzalez, Ghadbane, Knight, ODwyer, Overton, Lucato, Smith, Reis, Page, Whaley, McCully, Hearty, Mahon, Weber: "Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors." in: JCI insight, Vol. 6, Issue 20, (2021) (PubMed).

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Wang, Kang, Chen, Jehng, Jones, Chen, Huang, Chen: "An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses." in: Nature communications, Vol. 11, Issue 1, pp. 1395, (2020) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Wang, Fei, Jing, Wu, Wu, Zhou, Ni, Chen, Xiong, Liu, Peng, Yu, Jiang, Liu: "Durable blockade of PD-1 signaling links preclinical efficacy of sintilimab to its clinical benefit." in: mAbs, (2019) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Galstyan, Markman, Shatalova, Chiechi, Korman, Patil, Klymyshyn, Tourtellotte, Israel, Braubach, Ljubimov, Mashouf, Ramesh, Grodzinski, Penichet, Black, Holler, Sun, Ding, Ljubimov, Ljubimova: "Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy." in: Nature communications, Vol. 10, Issue 1, pp. 3850, (2019) (PubMed).

Aliase für PD-1 Proteine

programmed cell death 1 (PDCD1) Proteine
programmed cell death 1 (Pdcd1) Proteine
CD279 Proteine
hPD-1 Proteine
hPD-l Proteine
Ly101 Proteine
PD-1 Proteine
PD1 Proteine
Pdc1 Proteine
SLEB2 Proteine

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Target information, Synonyms, Latest references

Aktuelle Publikationen für unsere PD-1 Proteine

Aliase für PD-1 Proteine

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