anti-PPP1R13B (PPP1R13B) Antikörper

Bezeichnung:: anti-Protein Phosphatase 1, Regulatory Subunit 13B Antikörper (PPP1R13B)

Auf www.antikoerper-online.de finden Sie aktuell 62 Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Antikörper von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PPP1R13B Proteine (4) und PPP1R13B Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 74 PPP1R13B Produkte verfügbar.

Synonyme:: AI449786, ASPP1, AW545810, p53BP2-like, p85, pp2ca1, ppp1r13b, si:ch211-253p18.1, Tp53bp2, Trp53bp2, wu:fd42g12, zgc:153820

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	PPP1R13B	21981	Q62415
	PPP1R13B	23368	Q96KQ4
	PPP1R13B	314465
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-PPP1R13B (PPP1R13B) Antikörper

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anti-Mouse (Murine) PPP1R13B Antikörper:

anti-Human PPP1R13B Antikörper:

anti-Rat (Rattus) PPP1R13B Antikörper:

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Verknüpfte Pathways mit anti-PPP1R13B Antikörper

p53 Signalweg

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Am meisten referenzierte anti-PPP1R13B Antikörper

Human Polyclonal PPP1R13B Primary Antibody für IHC, ELISA - ABIN1584021 : Matsumoto, Weckbecker, Cory: Antineoplastic effect of the combination of 2,3-dihydro-1H-pyrazole[2,3a]imidazole plus deoxyadenosine/erythro-9-(2-hydroxyl-3-nonyl)adenine in mice with L1210 leukemia cells. in Cancer communications 1990 (PubMed)
Show all 2 Pubmed References
Human Polyclonal PPP1R13B Primary Antibody für IF (p), IHC (p) - ABIN674379 : Xie, Yang, Chi, Yang, Wang, Xu: Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study. in Chinese journal of cancer 2017 (PubMed)

Weitere Antikörper gegen PPP1R13B Interaktionspartner

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Interaktionspartner

After genotoxic stress, Aspp1 promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) cycling and induces p53 (zeige TP53 Antikörper)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 also attenuates HSC (zeige FUT1 Antikörper) self-renewal and accumulation of DNA damage in p53 (zeige TP53 Antikörper) null HSCs.
Our study demonstrates a novel role for ASPP1 and ASPP2 (zeige TP53BP2 Antikörper) in the death of retinal ganglion cells.
Aspp1 plays a crucial role in the initial assembly and function of lymphatic vessels during mouse development in a p53 (zeige TP53 Antikörper)-independent manner.

Human Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Interaktionspartner

results provide new insights into EGR-1 (zeige EGR1 Antikörper)/ASPP1 regulatory loop in sensitizing Quercetin-induced apoptosis. EGR-1 (zeige EGR1 Antikörper)/ASPP1, therefore, may be potentially used as therapeutic targets to improve cancer's response to pro-apoptosis treatments.
Results showed that the protein expression levels of ASPP1 in esophageal squamous cell carcinoma (ESCC) tissues and in paired noncancerous tissues were similar but was significantly associated with histological differentiation and invasive depth which suggest that it might be involved in the progression of ESCC.
Increased expression of p53 (zeige TP53 Antikörper) and ASPP1 and downregulation of iASPP (zeige PPP1R13L Antikörper).
ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.
ASPP1/2 interacted with centrosome linker protein (zeige LAT Antikörper) C (zeige PROC Antikörper)-Nap1 (zeige CEP250 Antikörper). Co-depletion of ASPP1 and ASPP2 (zeige TP53BP2 Antikörper) inhibited re-association of C-Nap1 (zeige CEP250 Antikörper) with centrosome at the end of mitosis.
ASPP1 and ASPP2 (zeige TP53BP2 Antikörper) cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53 (zeige TP53 Antikörper).
When the Px(T)PxR (zeige NR1I2 Antikörper) motif is deleted or mutated via insertion of a phosphorylation site mimic (T311D), PP-1c fails to bind to all three ASPP proteins, ASPP1, ASPP2 (zeige TP53BP2 Antikörper) and iASPP (zeige PPP1R13L Antikörper).
the mRNA expression of ASPP1 and ASPP2 (zeige TP53BP2 Antikörper) was frequently dowregulated in tumor tissues, and this decreased significantly in samples expressing wild-type p53 (zeige TP53 Antikörper)
ASPP1 promoter methylation may be associated with the malignant progression of non-small cell lung cancer, and ASPP1 expression promotes cellular apoptosis.
The ability of ASPP1 to activate YAP (zeige YAP1 Antikörper) results in the decreased expression of LATS2 (zeige LATS2 Antikörper), which lowers the ability of p53 (zeige TP53 Antikörper) to induce p21 (zeige CDKN1A Antikörper), cell-cycle arrest and senescence.

PPP1R13B Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Alternative names and synonyms associated with PPP1R13B

protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab) Antikörper
protein phosphatase 1 regulatory subunit 13B (PPP1R13B) Antikörper
protein phosphatase 1 regulatory subunit 13B (ppp1r13b) Antikörper
protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) Antikörper
protein phosphatase 1, regulatory subunit 13Bb (ppp1r13bb) Antikörper
protein phosphatase 1 regulatory subunit 13B L homeolog (ppp1r13b.L) Antikörper
protein phosphatase 1, regulatory subunit 13B (Ppp1r13b) Antikörper

AI449786 Antikörper
ASPP1 Antikörper
AW545810 Antikörper
p53BP2-like Antikörper
p85 Antikörper
pp2ca1 Antikörper
ppp1r13b Antikörper
si:ch211-253p18.1 Antikörper
Tp53bp2 Antikörper
Trp53bp2 Antikörper
wu:fd42g12 Antikörper
zgc:153820 Antikörper

Bezeichner auf Proteinebene für PPP1R13B

protein phosphatase type 2C alpha 1 , protein phosphatase 1, regulatory (inhibitor) subunit 13B , apoptosis-stimulating protein of p53, 1 , apoptosis-stimulating of p53 protein 1-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53 binding protein, 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating protein of p53

GENE ID	SPEZIES
30703	Danio rerio
423487	Gallus gallus
453193	Pan troglodytes
490874	Canis lupus familiaris
700432	Macaca mulatta
100020778	Monodelphis domestica
100060064	Equus caballus
100357525	Oryctolagus cuniculus
100380068	Xenopus (Silurana) tropicalis
100395359	Callithrix jacchus
100438788	Pongo abelii
100481667	Ailuropoda melanoleuca
100539199	Meleagris gallopavo
21981	Mus musculus
557278	Danio rerio
23368	Homo sapiens
496341	Xenopus laevis
511414	Bos taurus
314465	Rattus norvegicus

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Show all anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Antikörper with Pubmed References

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Interaktionspartner

Human Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with PPP1R13B

Bezeichner auf Proteinebene für PPP1R13B