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anti-CHEK2 Antikörper

266 Treffer:

anti-CHEK2 Antikörper (Checkpoint Kinase 2) Primary Antibody

CHEK2 Reaktivität: Human, Maus, Ratte IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed 2
Produktnummer ABIN3023035
528,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 7 bis 8 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (AA 111-141) Primary Antibody

CHEK2 Reaktivität: Human FACS, IF, IHC (p), WB Wirt: Kaninchen Polyclonal RB19067 unconjugated
Pubmed 5
Produktnummer ABIN1881196
409,99 €
Zzgl. Versandkosten 20,00 € und MwSt
400 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 14 bis 16 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (AA 1-543) Primary Antibody

CHEK2 Reaktivität: Human IP, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN950070
556,80 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL
local_shipping Lieferung nach: Deutschland
Lieferung in 8 bis 9 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (AA 1-543) Primary Antibody

CHEK2 Reaktivität: Human IF, IHC (p), ELISA, WB Wirt: Maus Monoclonal 4B7 unconjugated
Produktnummer ABIN564867
571,20 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
local_shipping Lieferung nach: Deutschland
Lieferung in 8 bis 9 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (pThr383) Primary Antibody

CHEK2 Reaktivität: Human, Maus, Ratte ELISA, ICC, IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256552
634,96 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 5 bis 6 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (pSer516) Primary Antibody

CHEK2 Reaktivität: Human, Maus, Ratte ELISA, ICC, IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6255391
634,96 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 5 bis 6 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (pThr68) Primary Antibody

CHEK2 Reaktivität: Human, Maus, Ratte ELISA, ICC, IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256592
634,96 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 5 bis 6 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) (pThr387) Primary Antibody

CHEK2 Reaktivität: Human, Maus, Ratte ELISA, ICC, IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256554
634,96 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL (More quantities available)
local_shipping Lieferung nach: Deutschland
Lieferung in 5 bis 6 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) Primary Antibody

CHEK2 Reaktivität: Human, Hund FACS, IHC, IHC (p), IP, WB Wirt: Maus Monoclonal 2H5 unconjugated
Produktnummer ABIN1497497
664,99 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL
local_shipping Lieferung nach: Deutschland
Lieferung in 15 bis 19 Werktagen

anti-CHEK2 Antikörper (Checkpoint Kinase 2) Primary Antibody

CHEK2 Reaktivität: Human, Hund, Affe FACS, IF, IHC, IHC (p), WB Wirt: Maus Monoclonal 10G7 unconjugated
Produktnummer ABIN1497495
664,99 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL
local_shipping Lieferung nach: Deutschland
Lieferung in 15 bis 19 Werktagen
  • Typ Primary
    • Primary
  • Target Checkpoint Kinase 2 (CHEK2)
    • Checkpoint Kinase 2 (CHEK2)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-kB p65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • CD8a Molecule (CD8A)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • CD19 Molecule (CD19)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Integrin alpha M (ITGAM)
    • CD3 epsilon (CD3E)
    • Tuberous Sclerosis 2 (TSC2)
    • CD44
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD3
    • Hemagglutinin (HA)
    • CD8
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Histone H4
    • Jun Proto-Oncogene (JUN)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Myc Proto-Oncogene protein (MYC)
    • CD5
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD34
    • Interleukin 2 (IL2)
    • Catenin, beta (CATNB)
    • CD14
    • Vimentin (VIM)
    • Mucin 1 (MUC1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Insulin Receptor Substrate 1 (IRS1)
    • Keratin 18 (KRT18)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Intercellular Adhesion Molecule 1 (ICAM1)
  • Anwendung
    • Western Blotting (WB)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunoprecipitation (IP)
    • Flow Cytometry (FACS)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunochromatography (IC)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Luminex Assay (LMNX)
    • Proximity Ligation Assay (PLA)
  • Reaktivität
    • Human
    • Maus
    • Ratte
    • Affe
    • Schwein
    • Rind (Kuh)
    • Drosophila melanogaster
    • Hund
    • Pferd
    • Kaninchen
    • Zebrafisch (Danio rerio)
    • Fledermaus
    • Huhn
    • Meerschweinchen
    • Schaf
    • Xenopus laevis
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Preservative free only
  • Wirt
    • Kaninchen
    • Maus
    • Ziege
    • Huhn
    • Schaf
  • Klonalität
    • Polyclonal
    • Monoclonal
  • Klon
    • 1C12B8
    • 20A8
    • 2CHK01
    • 2H5
    • 4B7
    • 5C4
    • 10G7
    • 2F4
    • 2T8
    • 6B8
    • 7A4
    • 7F9
    • 8F12
    • DCS-270
    • OTI2F4
    • RB19067
  • Bindungsspezifität
    • pThr68
    • pSer516
    • pThr387
    • pSer33
    • pSer19
    • pSer35
    • AA 120-160
    • AA 50-90
    • N-Term
    • AA 1-543
    • C-Term
    • pSer379
    • pThr432
    • pSer28
    • pThr26
    • pThr383
    • AA 133-148
    • AA 2-18
    • AA 64-73
    • Center
    • Ser516
    • Thr68
    • AA 10-90
    • AA 111-141
    • AA 330-410
    • AA 427-441
    • AA 460-540
    • AA 481-531
    • Ser19
    • Thr383
    • Tyr594
    • AA 1-100
    • AA 1-108
    • AA 1-50
    • AA 1-544
    • AA 1-546
    • AA 101-250
    • AA 115-128
    • AA 208-543
    • AA 300-540
    • AA 35-84
    • AA 356-405
    • AA 361-410
    • AA 465-498
    • AA 475-525
    • AA 486-535
    • AA 514-518
    • Internal Region
    • Met381
    • Ser35
    Please use search to find more...
  • Konjugat
    • Unkonjugiert
    • Biotin
    • Alexa Fluor 750
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • FITC
    • HRP
    • Alexa Fluor 350
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • KLH
    • Magnetic Particles
    • PE
    • Sepharose
    • APC
    • Alkaline Phosphatase (AP)
  • Isotyp
    • IgG
    • IgG1
    • IgG2b
    • IgG1 kappa
    • IgG2a kappa
    • Ig Fraction
    • IgG2a
    • IgY
  • Format
    • Liquid
    • Lyophilized

CHEK2 Antigen-Profil

Protein Überblick

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CHEK2

  • checkpoint kinase 2 (CHEK2) Antikörper
  • checkpoint kinase 2 (chek2) Antikörper
  • checkpoint kinase 2 (Chek2) Antikörper
  • serine/threonine-protein kinase chk2 (MCYG_07308) Antikörper
  • checkpoint kinase 2 L homeolog (chek2.L) Antikörper
  • cds1 Antikörper
  • chek2 Antikörper
  • chk2 Antikörper
  • fa66f08 Antikörper
  • hCds1 Antikörper
  • hucds1 Antikörper
  • lfs2 Antikörper
  • pp1425 Antikörper
  • rad53 Antikörper
  • wu:fa66f08 Antikörper
  • zgc:55865 Antikörper

Bezeichner auf Proteinebene für CHEK2

CHK2 checkpoint homolog , cds1 homolog , checkpoint-like protein CHK2 , serine/threonine-protein kinase Chk2 , protein kinase CHK2 , checkpoint and tumor suppressor protein 2 , Cds1 homolog , Rad53 homolog , protein kinase Chk2 , CHK2 checkpoint homolog (S. pombe) , serine/threonine-protein kinase Chk2-like , serine/threonine-protein kinase chk2 , checkpoint kinase 2 L homeolog , protein kinase Cds1

GENE ID SPEZIES
11200 Homo sapiens
486338 Canis lupus familiaris
458733 Pan troglodytes
100192447 Sus scrofa
336998 Danio rerio
768913 Gallus gallus
50883 Mus musculus
114212 Rattus norvegicus
100059288 Equus caballus
100404949 Callithrix jacchus
100467146 Ailuropoda melanoleuca
100594542 Nomascus leucogenys
9226831 Arthroderma otae CBS 113480
398179 Xenopus laevis

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