PAFAH1B1 Produkte
(Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
Kategorien
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009].
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Ausgewählte PAFAH1B1 Kategorien
PAFAH1B1 Antikörper
High quality antibodies with extensive validation data.
PAFAH1B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PAFAH1B1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PAFAH1B1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
ELISA, IHC, WB
Validierungen
- (5)
Kat. Nr.
ABIN184751
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IF, WB
Validierungen
- (4)
Kat. Nr.
ABIN7269401
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IF, ELISA, WB
Validierungen
- (4)
Kat. Nr.
ABIN518586
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PAFAH1B1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969386
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1148326
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1148327
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PAFAH1B1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3093548
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3134596
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313893
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PAFAH1B1 Produkten
: "Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex." in: Journal of proteome research, Vol. 12, Issue 11, pp. 5233-45, (2013) (PubMed).: "Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 3, pp. 585-92, (2012) (PubMed).
: "Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]." in: American journal of human genetics, Vol. 88, Issue 5, pp. 536-47, (2011) (PubMed).
: "Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning." in: Journal of cell science, Vol. 123, Issue Pt 2, pp. 202-12, (2010) (PubMed).
: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).
: "Neuronal migration in developmental disorders." in: Journal of child neurology, Vol. 20, Issue 4, pp. 280-6, (2005) (PubMed).
: "APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment." in: Molecular biology of the cell, Vol. 16, Issue 10, pp. 4609-22, (2005) (PubMed).
: "LIS2, gene and pseudogene, homologous to LIS1 (lissencephaly 1), located on the short and long arms of chromosome 2." in: Genomics, Vol. 30, Issue 2, pp. 251-6, (1996) (PubMed).
: "Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]." in: Nature, Vol. 370, Issue 6486, pp. 216-8, (1994) (PubMed).
: "Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats." in: Nature, Vol. 364, Issue 6439, pp. 717-21, (1993) (PubMed).
Synonyme und alternative Namen zu PAFAH1B1
platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1), platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Pafah1b1), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (Pafah1b1), platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog (pafah1b1.L), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a (pafah1b1a), platelet activating factor acetylhydrolase 1b regulatory subunit 1 (Pafah1b1), LIS-1, LIS1, Lis1, LIS2, lis2, MDCR, mdcr, MDS, mds, Mdsh, MMS10-U, Ms10u, PAFAH, pafah, pafah1b1-b, Pafaha, PAFAHABezeichner auf Proteinebene für PAFAH1B1
- LIS-1
- PAF acetylhydrolase 45 kDa subunit
- PAF-AH 45 kDa subunit
- PAF-AH alpha
- PAFAH alpha
- lissencephaly 1 protein
- lissencephaly-1 protein
- platelet-activating factor acetylhydrolase IB subunit alpha
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
- platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
- platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
- platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
- PAF-AH beta
- platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)
- platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
- LIS1
- lissencephaly-1 homolog
- lissencephaly-1 homolog B
- chLIS1
- platelet-activating factor acetylhydrolase Ib-alpha subunit
- Miller-Dieker syndrome chromosome region
- Lissencephaly-1 protein
- platelet-activating factor acetylhydrolase isoform Ib alpha subunit
- lis1b
- lissencephaly-1 homolog A
- platelet-activating factor acetylhydrolase IB subunit alpha a
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