anti-F2R (F2R) Antikörper

Bezeichnung:: anti-Coagulation Factor II (thrombin) Receptor Antikörper (F2R)

Auf www.antikoerper-online.de finden Sie aktuell 190 Coagulation Factor II (thrombin) Receptor (F2R) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen F2R Kits (67) und F2R Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 281 F2R Produkte verfügbar.

Synonyme:: AI482343, Cf2r, EMK1, f2r-a, HTR, Par-1, par1, Par1b, ThrR, TR, TRGPC

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	F2R	2149	P25116
	F2R	25439
	F2R	14062	P30558
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human F2R Antikörper:

anti-Rat (Rattus) F2R Antikörper:

anti-Mouse (Murine) F2R Antikörper:

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Verknüpfte Pathways mit anti-F2R Antikörper

Weitere Produktkategorien zu F2R Antikörper

Am meisten referenzierte anti-F2R Antikörper

Human Monoclonal F2R Primary Antibody für IF, WB - ABIN968574 : Coughlin: How the protease thrombin talks to cells. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
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Human Polyclonal F2R Primary Antibody für IF (p), IHC (p) - ABIN728743 : Liu, Xie, Luo, Chen, Zhou, Xia, Chen, Zhou, Cao, Cao, Zhou: Identification of FLOT2 as a novel target for microRNA-34a in melanoma. in Journal of cancer research and clinical oncology 2014 (PubMed)
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Human Monoclonal F2R Primary Antibody für IF, WB - ABIN968573 : Nelken, Soifer, OKeefe, Vu, Charo, Coughlin: Thrombin receptor expression in normal and atherosclerotic human arteries. in The Journal of clinical investigation 1992 (PubMed)
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Human Polyclonal F2R Primary Antibody für WB - ABIN611146 : Gradin, Larsson, Marklund, Gullberg: Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells. in The Journal of cell biology 1998 (PubMed)
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Human Polyclonal F2R Primary Antibody für WB - ABIN2801899 : Shapiro, Trejo, Zeng, Coughlin: Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization. in The Journal of biological chemistry 1997 (PubMed)
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Human Monoclonal F2R Primary Antibody für ELISA, WB - ABIN969339 : Nakayama, Kawato, Watanabe, Ohtsuka, Yoshida, Yokomizo, Sakamoto, Kuru, Ohta, Hoshino, Yoshida, Ishida, Cho, Palme, Zhang, Lee, Watkins: MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model. in Bioorganic & medicinal chemistry letters 2003 (PubMed)
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Human Polyclonal F2R Primary Antibody für IHC, ELISA - ABIN1584987 : Jeffers, Owens, Koenig, Quaid, Pendurthi, Rao, Idell, Tucker: Thrombin down-regulates tissue factor pathway inhibitor expression in a PI3K/nuclear factor-κB-dependent manner in human pleural mesothelial cells. in American journal of respiratory cell and molecular biology 2015 (PubMed)
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Human Monoclonal F2R Primary Antibody für ELISA, ICC - ABIN4343604 : Gonda, Watanabe, Ohuchi, Higuchi: In vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots. in The Journal of biological chemistry 2010 (PubMed)
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Human Polyclonal F2R Primary Antibody für CyTOF, FACS - ABIN4899990 : Doni, Musso, Morone, Bastone, Zambelli, Sironi, Castagnoli, Cambieri, Stravalaci, Pasqualini, Laface, Valentino, Tartari, Ponzetta, Maina, Barbieri, Tremoli, Catapano, Norata, Bottazzi, Garlanda et al.: An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. ... in The Journal of experimental medicine 2015 (PubMed)
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Human Monoclonal F2R Primary Antibody für ELISA, WB - ABIN966804 : Heider, Schulze, Oswald, Henklein, Scheele, Kaufmann: PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. in Oncology research 2004 (PubMed)
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Weitere Antikörper gegen F2R Interaktionspartner

Human Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

we found that activation of the protease-activated receptor 1 (PAR1) induced secretion of TSLP (zeige TSLP Antikörper) by the corneal stromal cells... we proposed that TSLP (zeige TSLP Antikörper) might function as the link between increased protease activity and inflammatory responses or itch sensation in the
PAR-1 (zeige MARK2 Antikörper) in non-small-cell lung cancer is mainly expressed on cells that constitute the pulmonary tumor microenvironment, including vascular endothelial cells, macrophages and stromal fibroblasts.
thrombin (zeige F2 Antikörper) binding to PAR-1 (zeige MARK2 Antikörper) receptor activated Gi-protein/c (zeige PROC Antikörper)-Src (zeige SRC Antikörper)/Pyk2 (zeige PTK2B Antikörper)/EGFR (zeige EGFR Antikörper)/PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper)/p42/p44 (zeige PSMC6 Antikörper) MAPK (zeige MAPK3 Antikörper) cascade, which in turn elicited AP-1 (zeige FOSB Antikörper) activation and ultimately evoked MMP-9 (zeige MMP9 Antikörper) expression and cell migration in SK-N-SH cells.
this study demonstrates that TGFbeta (zeige TGFB1 Antikörper) is a positive regulator of PAR-1 (zeige MARK2 Antikörper) expression in A549 lung adenocarcinoma cells, which in turn increases the sensitivity of these cells to thrombin (zeige F2 Antikörper) signalling
Taken together, these results indicated that PAR1 (zeige MARK2 Antikörper) signalingmediated cJun (zeige JUN Antikörper) activation promotes early apoptosis of HUVEC cells induced by heat stress.
The DHA - naringenin hybrid presented triple antiplatelet activity simultaneously targeting PAR-1 (zeige MARK2 Antikörper), P2Y12 (zeige P2RY12 Antikörper) and COX-1 (zeige COX1 Antikörper) platelet activation pathways
Dabigatran increases platelet reactivity by enhancing the thrombin receptor density on platelets
Thrombin (zeige F2 Antikörper), via PAR1 (zeige MARK2 Antikörper) activation, synergistically augments LPS (zeige IRF6 Antikörper)-induced Human endometrial endothelial cells production of chemokines involved in immune cell recruitment and survival, suggesting a mechanism by which intrauterine abruption and bacterial infection may together be associated with an aggravated uterine inflammatory response.
EPCR (zeige PROCR Antikörper) occupancy recruits G-protein coupled receptor kinase 5 (zeige GRK5 Antikörper), thereby inducing beta-arrestin-2 (zeige ARRB2 Antikörper) biased PAR1 (zeige MARK2 Antikörper) signaling by both APC (zeige APC Antikörper) and thrombin (zeige F2 Antikörper). In
Data suggest that the abrogation of protease-activated receptor 1 (PAR1)-dependent signaling pathways may prove a promising strategy for gliomas.

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

Experimental TCDD-elicited steatohepatitis is associated with coagulation cascade activation and PAR-1 (zeige MARK2 Antikörper)-driven hepatic inflammation and fibrosis.
PAR1 in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta (zeige TGFB1 Antikörper) signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.
this study shows that poly I:C treated PAR-1 (zeige MARK2 Antikörper)-/- mice given the thrombin (zeige F2 Antikörper) inhibitor dabigatran etexilate exhibited less IFNbeta and CXCL10 (zeige CXCL10 Antikörper) expression in the spleen and plasma
Brain water content in the ipsilateral hemisphere and the tumor mass were significantly lower in PAR-1 (zeige MARK2 Antikörper) KO than WT mice at day 12 after implantation of glioma cells.
The results of this study suggested that polarized microglia occur dynamically after ICH (zeige ACE Antikörper) and that PAR-1 (zeige MARK2 Antikörper) plays a role in the microglia activation and polarization.
In this study, we found upregulation of several hemostasis-related genes, including the thrombin (zeige F2 Antikörper)-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper)-deleted MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells. Similar to the effect of Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper) deletion, PAR-1 (zeige MARK2 Antikörper) overexpression induced CDKN1A/p21 (zeige CDKN1A Antikörper) expression and attenuated proliferation in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells
our findings define a detrimental role of thrombin (zeige F2 Antikörper)-activated PAR-1 (zeige MARK2 Antikörper) in wound healing in mice with spinal cord injuries.
thrombin (zeige F2 Antikörper)/PAR-1 (zeige MARK2 Antikörper) interaction regulated MCP-1 (zeige CPT1B Antikörper), TF, MCSF (zeige CSF1 Antikörper) and IL-6 (zeige IL6 Antikörper) production.
Thrombin (zeige F2 Antikörper) upregulates LCN2 (zeige LCN2 Antikörper) through protease-activated receptor-1 activation and causes brain damage.
Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (zeige MMP1 Antikörper)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

Thrombin (zeige F2 Antikörper) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (zeige RHOA Antikörper), and myocardin (zeige MYOCD Antikörper).
Thrombin (zeige F2 Antikörper) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (zeige CA2 Antikörper)+).

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

MMP-1 (zeige MMP1 Antikörper) promotes VEGFR2 (zeige KDR Antikörper) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (zeige NFKB1 Antikörper)
PAR1 and PAR2 (zeige F2RL1 Antikörper) regulate endothelial NO synthase (zeige NOS Antikörper) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

F2R Antigen-Profil

Beschreibung des Gens

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.

Alternative names and synonyms associated with F2R

coagulation factor II thrombin receptor (F2R) Antikörper
coagulation factor II (thrombin) receptor (F2r) Antikörper
microtubule affinity regulating kinase 2 (MARK2) Antikörper
coagulation factor 2 (thrombin) receptor L homeolog (f2r.L) Antikörper
coagulation factor II thrombin receptor (F2r) Antikörper

AI482343 Antikörper
Cf2r Antikörper
EMK1 Antikörper
f2r-a Antikörper
HTR Antikörper
Par-1 Antikörper
par1 Antikörper
Par1b Antikörper
ThrR Antikörper
TR Antikörper
TRGPC Antikörper

Bezeichner auf Proteinebene für F2R

protease-activated receptor 1 , proteinase-activated receptor 1 , PAR-1 , Thrombin receptor , coagulation factor II receptor , thrombin receptor , protease-activated receptor-1 , coagulation factor II (thrombin) receptor

GENE ID	SPEZIES
2149	Homo sapiens
25439	Rattus norvegicus
483769	Canis lupus familiaris
14062	Mus musculus
100521609	Sus scrofa
526585	Bos taurus
378526	Xenopus laevis
100719323	Cavia porcellus

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