anti-Deltex Homolog 4 (DTX4) Antikörper

Bezeichnung:: anti-Deltex Homolog 4 (Drosophila) Antikörper (DTX4)

Auf www.antikoerper-online.de finden Sie aktuell 25 Deltex Homolog 4 (Drosophila) (DTX4) Antikörper von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Deltex Homolog 4 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 31 Deltex Homolog 4 Produkte verfügbar.

Synonyme:: AI449438, BC044798, CD135, D930042H13, FLK-2, FLK2, LRRGT00037, RNF155, STK1, zgc:163052

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	DTX4	2322	P36888
	DTX4	207521	Q6PDK8
	DTX4	293774
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human Deltex Homolog 4 Antikörper:

anti-Mouse (Murine) Deltex Homolog 4 Antikörper:

anti-Rat (Rattus) Deltex Homolog 4 Antikörper:

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Verknüpfte Pathways mit anti-Deltex Homolog 4 Antikörper

Notch Signalweg

Weitere Produktkategorien zu Deltex Homolog 4 Antikörper

Weitere Antikörper gegen Deltex Homolog 4 Interaktionspartner

Human Deltex Homolog 4 (Drosophila) (DTX4) Interaktionspartner

Notch (zeige NOTCH1 Antikörper) is ligand activated and undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 (zeige ADAM10 Antikörper) processing
FLT3 (zeige FLT3 Antikörper) cell-surface expression did not vary by FLT3 (zeige FLT3 Antikörper) mutational status, but high FLT3 (zeige FLT3 Antikörper) expression was strongly associated with KMT2A (zeige MLL Antikörper) rearrangements. Our study found that there was no prognostic significance of FLT3 (zeige FLT3 Antikörper) cell surface expression in pediatric Acute Myeloid Leukemia (zeige BCL11A Antikörper)
DNA mutational analysis in FLT3 (zeige FLT3 Antikörper) in acute myeloid leukemia (zeige BCL11A Antikörper).
data confirm MLL (zeige MLL Antikörper)-PTD (zeige BCS1L Antikörper) and, to a lesser extent, FLT3 (zeige FLT3 Antikörper)-ITD as common events in +11 AML (zeige RUNX1 Antikörper).6, 7, 8 However, the high mutation frequencies of U2AF1 (zeige U2AF1 Antikörper) and genes involved in methylation (DNMT3A (zeige DNMT3A Antikörper), IDH2 (zeige IDH2 Antikörper)) have hitherto not been reported in +11 AML (zeige RUNX1 Antikörper)
The cytokine Fms-like tyrosine kinase 3 ligand is an important regulator of hematopoiesis. Its receptor, Flt3 (zeige FLT3 Antikörper), is expressed on myeloid, lymphoid and dendritic cell progenitors and is considered an important growth and differentiation factor for several hematopoietic lineages. [review]
FLT3 (zeige FLT3 Antikörper) amplification in solid cancers is infrequently observed using targeted genomic profile, as yet, FLT3 (zeige FLT3 Antikörper) amplification does not seem to be an actionable target or a proper biomarker for FLT3 (zeige FLT3 Antikörper) inhibitor sensitivity.
FLT3 (zeige FLT3 Antikörper) has a role in cytarabine transport by SLC29A1 (zeige SLC29A1 Antikörper) in pediatric acute leukemia
Data indicate a pathway MYSM1 (zeige MYSM1 Antikörper)/miR (zeige MLXIP Antikörper)-150/FLT3 (zeige FLT3 Antikörper) that inhibits proliferation of B1a cells, which may be involved in the pathogenesis of systemic lupus erythematosus (SLE).
findings confirm that FLT3 (zeige FLT3 Antikörper)-ITD-location influences disease biology and leads to changes in global gene expression. In our model, ITD-location alters proliferative capacity and sensitivity to FLT3 (zeige FLT3 Antikörper)-TKI-treatment in vivo
a decision analysis comparing allo-HCT vs chemotherapy in first complete remission for patients with cytogenetically intermediate-risk acute myeloid leukemia (zeige BCL11A Antikörper), depending on the presence or absence of FLT3 (zeige FLT3 Antikörper)-ITD), NPM1 (zeige NPM1 Antikörper), and CEBPA (zeige CEBPA Antikörper) mutations showed that allo-HCT was a favored postremission strategy in patients with FLT3 (zeige FLT3 Antikörper)-ITD, and chemotherapy was favored in patients with biallelic CEBPA (zeige CEBPA Antikörper) mutations.

Mouse (Murine) Deltex Homolog 4 (Drosophila) (DTX4) Interaktionspartner

The results indicate that DTX4 stable knockdown inhibits adipogenesis of 3T3-L1 cells through inhibiting C/EBPalpha (zeige CEBPA Antikörper) and PPARgamma (zeige PPARG Antikörper), arresting mitotic clonal expansion and regulating Wnt (zeige WNT2 Antikörper) signaling pathway.

Deltex Homolog 4 (DTX4) Antigen-Profil

Beschreibung des Gens

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Alternative names and synonyms associated with Deltex Homolog 4 (DTX4)

fms related tyrosine kinase 3 (FLT3) Antikörper
deltex E3 ubiquitin ligase 4 (DTX4) Antikörper
deltex 4, E3 ubiquitin ligase (Dtx4) Antikörper
deltex 4, E3 ubiquitin ligase (dtx4) Antikörper
deltex E3 ubiquitin ligase 4 (Dtx4) Antikörper

AI449438 Antikörper
BC044798 Antikörper
CD135 Antikörper
D930042H13 Antikörper
FLK-2 Antikörper
FLK2 Antikörper
LRRGT00037 Antikörper
RNF155 Antikörper
STK1 Antikörper
zgc:163052 Antikörper

Bezeichner auf Proteinebene für DTX4

CD135 antigen , FL cytokine receptor , STK-1 , fetal liver kinase 2 , fms-like tyrosine kinase 3 , growth factor receptor tyrosine kinase type III , receptor-type tyrosine-protein kinase FLT3 , stem cell tyrosine kinase 1 , deltex 4 homolog , E3 ubiquitin-protein ligase DTX4 , RING finger protein 155 , deltex4 , protein deltex-4 , deltex 4, E3 ubiquitin ligase , deltex homolog 4 , LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase DTX4

GENE ID	SPEZIES
2322	Homo sapiens
528508	Bos taurus
23220	Homo sapiens
207521	Mus musculus
100037355	Danio rerio
100723700	Cavia porcellus
293774	Rattus norvegicus
483461	Canis lupus familiaris
100066645	Equus caballus
100517143	Sus scrofa
100346085	Oryctolagus cuniculus

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