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Deltex Homolog 4 Antikörper (AA 230-280)

DTX4 Reaktivität: Human, Maus ELISA, WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6992091
  • Target Alle Deltex Homolog 4 (DTX4) Antikörper anzeigen
    Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
    Bindungsspezifität
    • 14
    • 7
    • 5
    • 3
    • 1
    AA 230-280
    Reaktivität
    • 23
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser Deltex Homolog 4 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 16
    • 7
    • 7
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    DTX4 antibody is human and mouse reactive. At least two isoforms of DTX4 are known to exist, this antibody will detect both isoforms. DTX4 antibody is predicted to not cross-react with other DTX protein family members.
    Aufreinigung
    DTX4 antibody is affinity chromatography purified via peptide column.
    Immunogen
    DTX4 antibody was raised against a 19 amino acid peptide near the center of human DTX4. The immunogen is located within amino acids 230 - 280 of DTX4.
    Isotyp
    IgG
    Top Product
    Discover our top product DTX4 Primärantikörper
  • Applikationshinweise
    DTX4 antibody can be used for detection of DTX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    DTX4 antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    DTX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
    Andere Bezeichnung
    DTX4 (DTX4 Produkte)
    Synonyme
    RNF155 antikoerper, AI449438 antikoerper, BC044798 antikoerper, D930042H13 antikoerper, zgc:163052 antikoerper, LRRGT00037 antikoerper, deltex E3 ubiquitin ligase 4 antikoerper, deltex 4, E3 ubiquitin ligase antikoerper, DTX4 antikoerper, Dtx4 antikoerper, dtx4 antikoerper
    Hintergrund
    The Deltex 4 E3 ubiquitin ligase (DTX4) is a member of a protein family that is involved in Notch signaling and neurogenesis (1). Recent studies have shown that DTX4 is also associated with the innate immune response (2). Following the activation of type I interferon signaling, the Nod-like receptor protein 4 (NLRP4) recruits DTX4 for Lys48-linked polyubiquitination and degradation of the kinase TBK1 (NAK), thereby maintaining immune homeostasis during antiviral innate immunity (2).
    Molekulargewicht
    Predicted: 68 kDa

    Observed: 68 kDa
    Gen-ID
    23220
    NCBI Accession
    NP_055992
    UniProt
    Q9Y2E6
    Pathways
    Notch Signalweg
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