anti-Tumor Necrosis Factor (TNF) Antikörper

Bezeichnung:: anti-Tumor Necrosis Factor Antikörper (TNF)

Auf www.antikoerper-online.de finden Sie aktuell 1850 Tumor Necrosis Factor (TNF) Antikörper von 53 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Kits (363) und Tumor Necrosis Factor Proteine (262) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 2506 Tumor Necrosis Factor Produkte verfügbar.

Synonyme:: Cachectin, cTNF, dif, RATTNF, tnf, TNF-a, tnf-alpha, tnfa, tnfa-like, TNFalpha, Tnfsf1a, tnfsf2, xtnf

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TNF	7124	P01375
Anti-Ratte TNF	TNF	24835	P16599
	TNF	21926	P06804
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Am meisten referenzierte anti-Tumor Necrosis Factor Antikörper

Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody für CyTOF, ELISA (Capture) - ABIN4900489 : Ramkhelawon, Hennessy, Ménager, Ray, Sheedy, Hutchison, Wanschel, Oldebeken, Geoffrion, Spiro, Miller, McPherson, Rayner, Moore: Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. in Nature medicine 2014 (PubMed)
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Rat (Rattus) Polyclonal Tumor Necrosis Factor Primary Antibody für WB - ABIN3042522 : Zhang, Liu, Goldstein, Li, Ge, He, Fei, Wang, Ruiz: Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-?B expression. in Molecular medicine reports 2013 (PubMed)
Show all 38 Pubmed References
Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody für WB - ABIN3043313 : Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013 (PubMed)
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Human Polyclonal Tumor Necrosis Factor Primary Antibody für IHC (p), WB - ABIN4886747 : Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015 (PubMed)
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Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody für ELISA, IHC (p) - ABIN3042817 : Kan, Zhou, Jin, Yang: Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury. in International journal of clinical and experimental medicine 2015 (PubMed)
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Human Monoclonal Tumor Necrosis Factor Primary Antibody für - ABIN1383955 : Hervé, Racadot, Wijdenes, Flesch, Tiberghien, Bordigoni, Holler, Powles, Bourdeau, Wilmer: Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody. in Bone marrow transplantation 1991 (PubMed)
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Human Polyclonal Tumor Necrosis Factor Primary Antibody für ICC, IF - ABIN446837 : Kwon, Jung, Hwang, Choi: Evaluation of Bronchiolar and Alveolar Cell Injuries Induced by Short- and Long-term Exposure to Sidestream Smoke. in Korean journal of pathology 2012 (PubMed)
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Human Polyclonal Tumor Necrosis Factor Primary Antibody für IF (p), IHC (p) - ABIN677318 : Morishita, Oku, Horie, Tonari, Kida, Okubo, Sugiyama, Takai, Hara, Ikeda: Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-?B activation. in PLoS ONE 2014 (PubMed)
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Human Polyclonal Tumor Necrosis Factor Primary Antibody für IHC (p), IHC - ABIN153474 : Roth, Städler, Lemann, Hösli, Simon, Simon: Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. in Allergy 2011 (PubMed)
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Human Polyclonal Tumor Necrosis Factor Primary Antibody für ELISA, ICC - ABIN6269443 : Feng, Cui, Gao, Li, Li, Jiang, Tian, Wang, Cui, Cui: Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury. in International journal of molecular medicine 2016 (PubMed)
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Weitere Antikörper gegen Tumor Necrosis Factor Interaktionspartner

Human Tumor Necrosis Factor (TNF) Interaktionspartner

this is the first evidence to suggest that TET2 (zeige TET2 Antikörper) mutations promote clonal dominance with aging by conferring TNFalpha resistance to sensitive bone marrow progenitors while also propagating such an inflammatory environment.
Anti-rotavirus effect of TNF-alpha was achieved by NFkappaB (zeige NFKB1 Antikörper)-regulated genes via the activation of classical nuclear factor kappaB (NF-kappaB (zeige NFKB1 Antikörper)) signaling.
Results revealed that heterozygous genotype GA of TNF-alpha-238 (rs 361525) SNP significantly increased the risk of adverse-outcome (mortality rate), regardless of organ dysfunction or severity of sepsis.
in the patients with primary depression, depressive symptoms were associated with TNF-alpha
Addition of TNFalpha to podocytes causes CD80 upregulation, actin reorganization and podocyte injury.
The results of the study suggest that the levels of C-reactive protein (zeige CRP Antikörper) and tumor necrosis factor-alpha are important diagnostic markers of inflammation in patients with chronic pancreatitis and type 2 diabetes mellitus.
TNF-alpha and IL-10 (zeige IL10 Antikörper) treatment can affect the expression of ICAM-1 (zeige ICAM1 Antikörper) and CD31 (zeige HBA1 Antikörper) in human coronary artery endothelial cells.
the results of the present study suggested that overexpression of KLF15 in Eahy926 cells exhibited a protective effect against TNFalpha induced dysfunction via activation of Nrf2 (zeige GABPA Antikörper) signaling and inhibition of nuclear factor kappaB signaling.
The present study demonstrated the ability of 30 and 100 ng/ml TIMP3 (zeige TIMP3 Antikörper) to attenuate migration and proliferation, and to inhibit the activity of MMP2 (zeige MMP2 Antikörper), MMP9 (zeige MMP9 Antikörper) and TNFalpha secretion of NA SMCs. In conclusion, TIMP3 (zeige TIMP3 Antikörper) may be considered a potential therapeutic drug for use in a novel drugeluting stent, to attenuate the progressive dilation of the aortic NA.
Elevated A20 (zeige TNFAIP3 Antikörper) promotes TNF-induced and RIPK1 (zeige RIPK1 Antikörper)-dependent intestinal epithelial cell death

Mouse (Murine) Tumor Necrosis Factor (TNF) Interaktionspartner

this is the first evidence to suggest that TET2 (zeige TET2 Antikörper) mutations promote clonal dominance with aging by conferring TNFalpha resistance to sensitive bone marrow progenitors while also propagating such an inflammatory environment.
Elevated A20 (zeige TNFAIP3 Antikörper) promotes TNF-induced and RIPK1 (zeige RIPK1 Antikörper)-dependent intestinal epithelial cell death
M. tuberculosis and TNFalpha synergise to induce necroptosis in murine fibroblasts via RIPK1-dependent mechanisms and characterized by phosphorylation of Ser345 of the MLKL necroptosis death effector.
Our current study has demonstrated that in allergic airway disease (AAD) mice, intestinal dysbiosis (ID) caused increased nasal rubbing, sneezing, serum OVA specific IgE level and pro-inflammatory cytokine TNF-alpha in NALF and BALF. ID also inhibited miR (zeige MLXIP Antikörper)-130a expression in AAD mice. Further molecular experiments indicated that miR (zeige MLXIP Antikörper)-130a could specifically target and repress TNF-alpha mRNA expression.
These data may indicate that insulin (zeige INS Antikörper) resistance in Adp(-/-) mice is likely caused by an increase in concentrations of TNFalpha and FFA via downregulation of PPARalpha (zeige PPARA Antikörper).
TNF-alpha is involved in cardiac PHLPP1 (zeige PHLPP1 Antikörper) upregulation during reoxygenation, which is mediated by NF-kappaB (zeige NFKB1 Antikörper) transcriptional activity
TRYP improves the health condition of mice with DSS (zeige PMP22 Antikörper) induced colitis by regulating the TNF-&alpha;/NF-κBp65 and IL-6 (zeige IL6 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling pathways via inhibiting the degradation of IκBα and the phosphorylation of STAT3 (zeige STAT3 Antikörper).
Lack of TNF-alpha signaling through Tnfr1 (zeige TNFRSF1A Antikörper) makes the mice more susceptible to acute infection but does not alter state of latency and reactivation of HSV-1.
although TNFalpha does not induce osteoclastogenesis alone, it does work with RANKL to induce osteoclastic differentiation, and the NFkappaB pathway may serve an important role in this process.
two different modes of necroptosis induction by TNFalpha exist which are differentially regulated by iuRIPK1 formation. Overall, this work reveals a distinct mechanism of RIPK1 (zeige RIPK1 Antikörper) activation that mediates the signaling mechanism of RDA as well as a type of necroptosis.

Cow (Bovine) Tumor Necrosis Factor (TNF) Interaktionspartner

Data suggest that luteolytic factors (such as TNFa, interferon gamma (zeige IFNG Antikörper), and PGF2a) control expression of MMP1 (zeige MMP1 Antikörper), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
These results suggest that polymorphism of the TNFalpha-824 A>G gene and mTNFalpha protein expression play an important role in the pathogenesis of enzootic bovine leukosis.
These results suggest that the endometrium might lower the TNF concentration in the blastocyst by (1) regulating TNF secretion into the uterine fluid and (2) inducing decreased TNF and TNFR2 (zeige TNFRSF1B Antikörper) mRNA transcription in the embryo.
There was a significant association between the proviral load and a low frequency of the G/G genotype of TNF-alpha at position -824.
SNP in the TNF-alpha gene affects immune function and reproductive performance in dairy cows.
Studied genotypic and expression profiling of partial TNF-alpha gene and its association with mastitis susceptibility in 129 crossbred cattle.
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (zeige PTGES Antikörper)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF) and Fas (zeige FAS Antikörper) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
TNF-alpha up-regulates NaV1.7 (zeige SCN9A Antikörper) mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha
These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha and iNOS (zeige NOS2 Antikörper) pathways in the regulation of this pathological condition.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 Antikörper) and PTGS2 (zeige PTGS2 Antikörper), and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF and IL6 (zeige IL6 Antikörper) levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.

Pig (Porcine) Tumor Necrosis Factor (TNF) Interaktionspartner

these findings provide the direct evidence that ADAM17 (zeige ADAM17 Antikörper) cleaves porcine TNFalpha, which represents a new view for identifying potential therapeutic targets in anti-porcine reproductive and respiratory syndrome virus therapy
TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (zeige PDCD4 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)/ TNF-alpha pathway in cardiomyocytes.
TNF-alpha, secreted from activated Monocytes, mediates the downregulation of OTX2 (zeige OTX2 Antikörper) and essential retinal pigment epithelium genes.
TNF-alpha induced MMP-13 (zeige MMP13 Antikörper) expression by condylar cells might be involved in the degradation of the juvenile condyle.
TNF-alpha was able to promote theca interna cell proliferation. Our results suggest that TNF-alpha might play a role in hyperandrogenism, cortex thickness, and the increased ovary volume observed in polycystic ovaries.
This study showed that the -791(C-->T) mutation of the TNF-alpha gene could be considered an important potential genetic marker of enterotoxigenic Escherichia coli F18 (zeige MAMLD1 Antikörper) resistance.
Both Nsp1beta and Nsp11 of porcine reproductive and respiratory syndrome virus were demonstrated to be responsible for the inhibitory effect on TNF-alpha production in pulmonary alveolar macrophages.
Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (zeige IL1B Antikörper), IL-8 (zeige IL8 Antikörper) and TNF-alpha in porcine alveolar macrophages.
the role of miR (zeige MYLIP Antikörper)-181a in adipocyte differentiation by regulation of TNF-alpha
The NOS (zeige NOS Antikörper) inhibitor, L-NMMA, significantly suppressed the combined effects of HT and CORM-2 on TNFalpha-triggered NFkappaBp65 phosphorylation as well as decreased cell viability.

Zebrafish Tumor Necrosis Factor (TNF) Interaktionspartner

Mecp2 is required for tnfa expression during zebrafish development and inflammation.
Using in vivo, time-lapse imaging we show that as centrally-projecting pioneer axons from dorsal root ganglia (DRG (zeige COL4A1 Antikörper)) enter the spinal cord, they initiate expression of the cytokine TNFalpha. This induction coincides with ensheathment of these axons by associated glia via a TNF receptor 2 (TNFR2 (zeige TNFRSF1B Antikörper))-mediated process.
The results reveal a crucial role for TNFalpha/TNFR2 (zeige TNFRSF1B Antikörper) axis in the protection of the skin against DUOX1 (zeige DUOX1 Antikörper)-mediated oxidative stress.
proinflammatory cytokines IL-1 (zeige IL1A Antikörper)/TNFalpha trigger a novel antiviral mechanism involving AID to regulate host cell permissiveness to HBV infection.
TNF alpha is the first molecule identified that is produced by dying retinal neurons and is necessary to induce Muller glia to proliferate in the zebrafish retinal regeneration response.
The data suggest that Mycobacterium marinum SecA2 modulates adaptive immunity to promote granuloma stability, perhaps through induction of tumor necrosis factor alpha.
The data suggest that during infectious pancreatic necrosis virus infection, the expression of cytokines and metalloproteinases might be initiated through the TNFalpha/NF-kappaB (zeige NFKB1 Antikörper)-mediated pathway.
Infectious pancreatic necrosis virus triggers two death pathways via up-stream induction of the pro-inflammatory cytokine TNFalpha.
Antisense knockdown of tnfa rescued hepatic steatosis and liver degeneration in dtp (zeige AHCY Antikörper) larvae, whereas the overexpression of tnfa and the hepatic phenotype were unchanged in dtp (zeige AHCY Antikörper) larvae.
TNF is not required for tuberculous granuloma formation, but maintains granuloma integrity indirectly by restricting mycobacterial growth within macrophages and preventing their necrosis.

Rhesus Monkey Tumor Necrosis Factor (TNF) Interaktionspartner

These interactions result in the induction of the TNF signaling pathway, activation of apoptosis, and DNA-damage stress response.
Findings showed that both mucosal compartments harbor similar percentages of memory CD4 (zeige CD4 Antikörper)(+) T cells and displayed comparable cytokine TNF-alpha responses to mitogenic stimulations prior to infection.
Primary role for IL-1beta (zeige IL1B Antikörper) and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.

Horse (Equine) Tumor Necrosis Factor (TNF) Interaktionspartner

The results obtained showed that IL-6 (zeige IL6 Antikörper) expression in adipose tissue biopsies derived from animals with equine metabolic syndrome was enhanced while TNF-alpha levels of both groups were comparable.
Data indicate that tumor necrosis factor-alpha production is closely related to ovarian steroid actions.
These results indicate that in equine corpus luteum, cytokines TNF, IFNG (zeige IFNG Antikörper) and FASL (zeige FASL Antikörper) regulate nitric oxide activity, via eNOS (zeige NOS3 Antikörper) expression modulation.
These data show the presence of cytokines TNF and IFNG (zeige IFNG Antikörper), and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (zeige IL6 Antikörper), IL-10 (zeige IL10 Antikörper) and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Rabbit Tumor Necrosis Factor (TNF) Interaktionspartner

TUNEL staining was positively correlated with TNF-a protein expression. Our findings suggest that apoptosis can be induced in the vocal fold epithelium after 120min of modal intensity phonation. In contrast, shorter durations of vibration exposure do not result in apoptosis signaling.
Inflammatory factors such as TNF-alpha can stimulate MMP-2 (zeige MMP2 Antikörper)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases.
The JNK (zeige MAPK8 Antikörper) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 (zeige IL8 Antikörper) expression may be regulated by other signaling pathways.
The TNFalpha-evoked Cl- current.
IL-1beta (zeige IL1B Antikörper) and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta (zeige IL1B Antikörper) and TNF-alpha.
Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models.
In the early stages of myocardial ischemia, bone marrow stem cells are mobilized and home to ischemic myocardium with a concomitant increase in expression of cytokines VEGF (zeige VEGFA Antikörper) and TNFalpha.
Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (zeige TGFB1 Antikörper)) and TNF-alpha in lung of rabbits.
TNFalpha may either be directly or indirectly involved in vascular damage following an embolic stroke. Moreover, TNFalpha may mediate some of the detrimental effects of tPA (zeige PLAT Antikörper) on the vascular compartment

Goat Tumor Necrosis Factor (TNF) Interaktionspartner

Data indicate that three single-nucleotide polymorphisms were identified in tumor necrosis factor-alpha (TNF-alpha) gene.

Cynomolgus Tumor Necrosis Factor (TNF) Interaktionspartner

Macrophage- and neutrophil-derived TNF-alpha instructs skin langerhans cells to prime antiviral immune responses.

Tumor Necrosis Factor (TNF) Antigen-Profil

Beschreibung des Gens

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Alternative names and synonyms associated with Tumor Necrosis Factor (TNF)

tumor necrosis factor (TNF) Antikörper
tumor necrosis factor (Tnf) Antikörper
tumor necrosis factor (tnf) Antikörper
tumor necrosis factor b (TNF superfamily, member 2) (tnfb) Antikörper
tumor necrosis factor alpha (tnf-alpha) Antikörper
tumor necrosis factor (LOC103694380) Antikörper
tumor necrosis factor a (TNF superfamily, member 2) (tnfa) Antikörper

Cachectin Antikörper
cTNF Antikörper
dif Antikörper
RATTNF Antikörper
tnf Antikörper
TNF-a Antikörper
tnf-alpha Antikörper
tnfa Antikörper
tnfa-like Antikörper
TNFalpha Antikörper
Tnfsf1a Antikörper
tnfsf2 Antikörper
xtnf Antikörper

Bezeichner auf Proteinebene für TNF

, , , , , , , , , , , , , , , , , , , , , , APC1 protein TNF, macrophage-derived TNF, monocyte-derived TNF-a cachectin tumor necrosis factor ligand superfamily member 2 tumor necrosis factor-alpha tumor necrosis factor (TNF superfamily, member 2) tumor necrosis factor alpha tumor necrosis factor TNF-alpha tumor-necrosis factor tumour necrosis factor TNF alpha TNF2 lta ATP-binding cassette, sub-family F (GCN20), member 1 tumour necrosis factor alpha tumor necrosis factor, alpha Cachectin Tumor necrosis factor ligand superfamily member 2 TNF-alpha 1 TNF1

GENE ID	SPEZIES
7124	Homo sapiens
24835	Rattus norvegicus
100136064	Oncorhynchus mykiss
100304592	Ictalurus punctatus
21926	Mus musculus
280943	Bos taurus
397086	Sus scrofa
403922	Canis lupus familiaris
443540	Ovis aries
554167	Danio rerio
715467	Macaca mulatta
100033834	Equus caballus
100134991	Xenopus (Silurana) tropicalis
100137091	Salmo salar
100397484	Callithrix jacchus
100135630	Cavia porcellus
100009088	Oryctolagus cuniculus
493755	Felis catus
101420445	Dasypus novemcinctus
494186	Pan troglodytes
101318178	Tursiops truncatus
100861232	Capra hircus
103694380	Rattus norvegicus
102139631	Macaca fascicularis
405785	Danio rerio
101687148	Mustela putorius furo

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