anti-TRAF6 (TRAF6) Antikörper

Bezeichnung:: anti-TNF Receptor-Associated Factor 6 Antikörper (TRAF6)

Auf www.antikoerper-online.de finden Sie aktuell 144 TNF Receptor-Associated Factor 6 (TRAF6) Antikörper von 31 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF6 Kits (20) und TRAF6 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 196 TRAF6 Produkte verfügbar.

Synonyme:: 2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TRAF6	22034	P70196
	TRAF6	7189	Q9Y4K3
	TRAF6	311245	B5DF45
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TRAF6 (TRAF6) Antikörper

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anti-Mouse (Murine) TRAF6 Antikörper:

anti-Human TRAF6 Antikörper:

anti-Rat (Rattus) TRAF6 Antikörper:

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Verknüpfte Pathways mit anti-TRAF6 Antikörper

Weitere Produktkategorien zu TRAF6 Antikörper

Am meisten referenzierte anti-TRAF6 Antikörper

Human Polyclonal TRAF6 Primary Antibody für WB - ABIN1881900 : Hinz, Stilmann, Arslan, Khanna, Dittmar, Scheidereit: A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. in Molecular cell 2010 (PubMed)
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Human Polyclonal TRAF6 Primary Antibody für ICC, ELISA - ABIN1003297 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)
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Cow (Bovine) Polyclonal TRAF6 Primary Antibody für IHC (fro), IHC (p) - ABIN537432 : Ichii, Otsuka, Sasaki, Namiki, Hashimoto, Kon: Altered expression of microRNA miR-146a correlates with the development of chronic renal inflammation. in Kidney international 2012 (PubMed)
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Human Polyclonal TRAF6 Primary Antibody für FACS, WB - ABIN4361690 : Yoshida, Jono, Kai, Li: The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7. in The Journal of biological chemistry 2005 (PubMed)
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Human Polyclonal TRAF6 Primary Antibody für ICC, IHC (fro) - ABIN3044469 : Yuan, Zhang, Yang: Ligusticum wallichii Extract Inhibited the Expression of IL-1? after AMI in Rats. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)
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Human Polyclonal TRAF6 Primary Antibody für IF (p) - ABIN918441 : Qi, Pradipta, Li, Zhao, Lu, Fu, Wei, Hsung, Tanaka, Zhou: Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6. in Journal of experimental & clinical cancer research : CR 2017 (PubMed)
Human Polyclonal TRAF6 Primary Antibody für IF (p), IHC (p) - ABIN738906 : Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway. in Scientific reports 2017 (PubMed)
Cow (Bovine) Polyclonal TRAF6 Primary Antibody für IHC, IHC (p) - ABIN4361692 : Zapata, Krajewska, Krajewski, Kitada, Welsh, Monks, McCloskey, Gordon, Kipps, Gascoyne, Shabaik, Reed: TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
Human Polyclonal TRAF6 Primary Antibody für ELISA, ICC - ABIN4361694 : Doyon, Servant et al.: Tumor necrosis factor receptor-associated factor-6 and ribosomal S6 kinase intracellular pathways link the angiotensin II AT1 receptor to the phosphorylation and activation of the IkappaB kinase ... in The Journal of biological chemistry 2010 (PubMed)

Weitere Antikörper gegen TRAF6 Interaktionspartner

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (zeige MAPK8 Antikörper) activity by dissociating Atg9 (zeige ATG9A Antikörper)/mAtg9 (zeige ATG9A Antikörper) from dTRAF2/TRAF6 in Drosophila.
null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

TRAF6 coiled-coil oligomerization domain primes its interaction with Ubc13 (zeige UBE2N Antikörper)/Ub~Ubc13 (zeige UBE2N Antikörper) to confer processivity. Long polyUb chain assembly requires coiled-coil domain of TRAF6
TRAF6 is a key promoter of ischemic signaling cascades and neuronal death after cerebral ischemia/reperfusion injury. TRAF6 upregulation binds and ubiquitinates Rac1 directly, which promotes neuron death through neuroinflammation and neuro-oxidative signals.
Data provide a novel association between WDFY3 (zeige WDFY3 Antikörper) and the RANKL (zeige TNFSF11 Antikörper)-induced osteoclastogenesis pathway via the modulation of TRAF6.
this study shows that TRAF6 is necessary for the nontranscriptional priming of NLRP3 (zeige NLRP3 Antikörper) inflammasome by TLR/IL-1R derived signals
work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (zeige TRAF1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)-regulated apoptosis and the p53 (zeige TP53 Antikörper)/PCNA (zeige PCNA Antikörper)- and ATM (zeige ATM Antikörper)/ATR (zeige ATR Antikörper)-Chk1 (zeige CHEK1 Antikörper)/2-controlled DNA-damage response pathways.
TRAF6 prevents the mitochondrial translocation of p53 (zeige TP53 Antikörper) and spontaneous apoptosis by promoting lysine63-linked ubiquitination of p53 (zeige TP53 Antikörper) in cytosol.
TRAF6 mediates lysine-63 ubiquitination within the SH2 (zeige MYO15 Antikörper) domain of STAT3 (zeige STAT3 Antikörper), which is an essential step for STAT3 (zeige STAT3 Antikörper) membrane recruitment and phosphorylation in response to S Typhimurium infection; results reveal a strategy in which S Typhimurium T3SS effectors broaden their functions through the activation of host proteins in a ubiquitination-dependent manner to manipulate host cells into becoming a Salmonella-friendly zone
this study shows that an interaction of TRAF6 with cullin-5 (zeige CUL5 Antikörper) promotes TRAF6 polyubiquitination and lipopolysaccharide signaling
Consistent with cellular studies, icaritin downregulated TRAF6 and NFATc1 protein expression in CD11b(+) /Gr-1(-/low) osteoclast precursors
Data (including data from studies using knockout mice) suggest that RANKL (zeige TNFSF11 Antikörper) enhances TNF (zeige TNF Antikörper)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 by degrading Traf3 (zeige TRAF3 Antikörper), a known inhibitor of osteoclastogenesis. (RANKL (zeige TNFSF11 Antikörper) = osteoclast differentiation factor (zeige TNFSF11 Antikörper); TNF (zeige TNF Antikörper) = tumor necrosis factor (zeige TNF Antikörper); Traf (zeige TRAF1 Antikörper) = TNF (zeige TNF Antikörper) receptor-associated factor)

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity
Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

miRNA146a expression was significantly higher in hepatitis C patients with a best cut off value 1.63 to discriminate between hepatitis C patients and healthy controls. Meanwhile, it was negatively correlated to IRAK1 (zeige IRAK1 Antikörper) and TRAF6 levels and positively correlated to viral load in hepatitis C patients.
Suggest role for EBV-EBER1 in the induction of increased TRAF6 expression in the peripheral B cells of Sjogren's patients.
theses results indicate that miR (zeige MLXIP Antikörper)-146b-5p inhibits tumor growth and metastasis of hepatocellular carcinoma by targeting TRAF6 mediated Akt (zeige AKT1 Antikörper) phosphorylation
TRAF6 plays direct roles in the pro-inflammatory effects and proliferation of Rheumatoid arthritis (RA) fibroblast-like synoviocytes. TRAF6 may serve as a potential treatment target in RA.
MiR (zeige MLXIP Antikörper)-146a declined, while TRAF6 increased in lupus nephritis patients compared with healthy controls.
Epigallocatechin-3-gallate is a novel E3 ubiquitin ligase (zeige MUL1 Antikörper) inhibitor that could be used to target TRAF6 activity in melanoma cells, inhibiting cell proliferation/migration.
Results identified TRAF6 as a direct target of miR (zeige MLXIP Antikörper)-429, and its downregulation partially attenuates the effect of miR (zeige MLXIP Antikörper)-429 in promoting hepatocellular carcinoma cell proliferation and motility.
Compared with normal chondrocytes, the expression of miR (zeige MLXIP Antikörper)-146a decreased, while the mRNA and protein expressions of TRAF6 and NF-kappaB (zeige NFKB1 Antikörper) increased in osteoarthritis chondrocytes.
We report two siblings with SCID (zeige PRKDC Antikörper) and an atypical phenotype of osteopetrosis (OP (zeige CSF1 Antikörper)). A biallelic microdeletion encompassing the 5' region of TRAF6, RAG1 (zeige RAG1 Antikörper) and RAG2 (zeige RAG2 Antikörper) genes was identified. TRAF6, a tumor necrosis factor (zeige TNF Antikörper) receptor-associated family member, plays an important role in T cell signaling and in RANKL (zeige TNFSF11 Antikörper)-dependent osteoclast differentiation and activation but its role in human OP has not been previously reported
miR (zeige MLXIP Antikörper)-146a improves intestine epithelial cells survival under ischemia and I/R injury through inhibition TLR4 (zeige TLR4 Antikörper), TRAF6, and p-IkappaBalpha (zeige NFKBIA Antikörper), subsequently leading to decreased NF-kappaB (zeige NFKB1 Antikörper) p65 (zeige GORASP1 Antikörper) nuclear translocation.

TRAF6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

TNF receptor associated factor 6 L homeolog (traf6.L) Antikörper
TNF-receptor-associated factor 6 (Traf6) Antikörper
TNF receptor associated factor 6 (TRAF6) Antikörper
TNF receptor associated factor 6 (traf6) Antikörper
TNF receptor-associated factor 6 (LOC551819) Antikörper
TNF receptor-associated factor 6 (traf6) Antikörper
TNF receptor-associated factor 6 (Traf6) Antikörper
TNF receptor associated factor 6 (Traf6) Antikörper

2310003F17Rik Antikörper
AI851288 Antikörper
C630032O20Rik Antikörper
CG10961 Antikörper
Dmel\\CG10961 Antikörper
dtraf2 Antikörper
dTRAF6 Antikörper
fi15f02 Antikörper
GB10539 Antikörper
MGC:3310 Antikörper
RNF85 Antikörper
TRAF Antikörper
Traf2 Antikörper
TRAF6 Antikörper
wu:fi15f02 Antikörper
xtraf6 Antikörper
zgc:63704 Antikörper

Bezeichner auf Proteinebene für TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

GENE ID	SPEZIES
444777	Xenopus laevis
31746	Drosophila melanogaster
423163	Gallus gallus
451702	Pan troglodytes
493524	Xenopus (Silurana) tropicalis
551819	Apis mellifera
100010055	Monodelphis domestica
100174890	Gasterosteus aculeatus
100395364	Callithrix jacchus
100449432	Pongo abelii
100510771	Anolis carolinensis
100544809	Meleagris gallopavo
100595327	Nomascus leucogenys
22034	Mus musculus
539124	Bos taurus
554561	Danio rerio
7189	Homo sapiens
311245	Rattus norvegicus
100688110	Canis lupus familiaris
396629	Sus scrofa
716907	Macaca mulatta

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