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anti-CD40 Ligand (CD40LG) Antikörper

Bezeichnung:: anti-CD40 Ligand Antikörper (CD40LG)

Auf www.antikoerper-online.de finden Sie aktuell 518 CD40 Ligand (CD40LG) Antikörper von 33 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CD40 Ligand Proteine (127) und CD40 Ligand Kits (111) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 778 CD40 Ligand Produkte verfügbar.

Synonyme:: CD40-L, Cd40l, CD154, gp39, hCD40L, HIGM1, IGM, IMD3, Ly-62, Ly62, T-BAM, Tnfsf5, TRAP

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CD40LG	959	P29965
	CD40LG	21947	P27548
	CD40LG	84349	Q9Z2V2
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Verknüpfte Pathways mit anti-CD40 Ligand Antikörper

Cancer Immune Checkpoints

Weitere Produktkategorien zu CD40 Ligand Antikörper

Am meisten referenzierte anti-CD40 Ligand Antikörper

Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für BR, IHC (fro) - ABIN2688993 : Carbone, Ruggiero, Terrazzano, Palomba, Manzo, Fontana, Spits, Kärre, Zappacosta: A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction. in The Journal of experimental medicine 1997 (PubMed)
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für BR, FACS - ABIN1176849 : DeKruyff, Gieni, Umetsu: Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für FACS - ABIN2688995 : Dunn, Luedecker, Haugen, Clegg, Farr: Thymic overexpression of CD40 ligand disrupts normal thymic epithelial organization. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für Func, ICC - ABIN1302930 : Wu, Zhou, Zheng, Liu: CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen. in The Journal of experimental medicine 1998 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für FACS, Func - ABIN1302520 : Fischbein, Ardehali, Yun, Schoenberger, Laks, Irie, Dempsey, Cheng, Fishbein, Bonavida: CD40 signaling replaces CD4+ lymphocytes and its blocking prevents chronic rejection of heart transplants. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody für Func, ICC - ABIN2749175 : Barnhart, Ford, Bhushan, Song, Covey: A polymorphic CD40 ligand (CD154) molecule mediates CD40-dependent signalling but interferes with the ability of soluble CD40 to functionally block CD154:CD40 interactions. in Immunology 2000 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody für Func, ICC - ABIN2752002 : Brams, Black, Padlan, Hariharan, Leonard, Chambers-Slater, Noelle, Newman: A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. in International immunopharmacology 2001 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody für FACS, Func - ABIN1302448 : Howard, Miga, Vanderlugt, Dal Canto, Laman, Noelle, Miller: Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. in The Journal of clinical investigation 1999 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody für Func, ICC - ABIN2749183 : Berner, Wolf, Hummel, Müller, Reuss-Borst: Increased expression of CD40 ligand (CD154) on CD4+ T cells as a marker of disease activity in rheumatoid arthritis. in Annals of the rheumatic diseases 2000 (PubMed)
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Baboon Monoclonal CD40 Ligand Primary Antibody für FACS - ABIN2688992 : Fuleihan, Ramesh, Horner, Ahern, Belshaw, Alberg, Stamenkovic, Harmon, Geha: Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. in The Journal of clinical investigation 1994 (PubMed)
Show all 4 Pubmed References

Weitere Antikörper gegen CD40 Ligand Interaktionspartner

Chimpanzee CD40 Ligand (CD40LG) Interaktionspartner

specific cross-linking with trimeric recombinant HIV-1 gp140 revealed reduced sensitivity for inhibition of CD154 up-regulation in chimpanzees, requiring fourfold higher concentrations of viral protein

Atlantic Salmon (Salmo salar) CD40 Ligand (CD40LG) Interaktionspartner

identification and functional characterization of CD40L and CD40 from Atlantic salmon (Salmo salar); results provide evidence for the existence of a functional CD40L mediated costimulatory pathway in Atlantic salmon

Human CD40 Ligand (CD40LG) Interaktionspartner

IL-17 and CD40L synergistically mediate the inflammatory response and remodelling associated with tissue injury and glomerular sclerosis in diabetic nephropathy
we describe, for the first time, the deleterious immunologic consequences of CD40LG duplication in a mother and son
increased expression levels of OX40 and OX40L were involved in the pathogenesis of Immune thrombocytopenia
the dependency of mantle cell lymphoma (MCL) cell lines on NFkappaB signaling and illustrated the ability of CD40L to activate the alternative NFkappaB pathway in MCL, was analyzed.
The decreased expression of CD40L in lymph nodes may be an important factor in tumor recurrence and progression in the oral squamous cell carcinoma patients.
Higher serum concentrations of sST2 and sCD40L in microvascular angina patients may be associated with inflammatory activation and coronary microvascular dysfunction.
associations between CD40L/IL-4 response and baseline ATM levels, induction of ATM, and phosphorylation of the ATM targets, p53 and H2AX. X-irradiation was used to demonstrate that CD40L/IL-4 stimulation tended to improve DNA damage repair.
Symptomatic chagasic patients were differentiated from asymptomatic patients based on the expression of CD154 and membrane TNF-alpha in TCD4+ and TCD8+ compartments, respectively.
the current study aimed to investigate the possible associations between CD40 polymorphisms and level of soluble CD154 protein with migraine.
this study reports the clinical and CD40L genetic features of six Iranian hyper IgM syndrome patients
the CD40 rs1883832 T allele acts as a risk factor for increased susceptibility to sepsis and may be involved in the process of sepsis through regulation of CD40 expression and plasma sCD40L levels.
Overexpression of CD40L-WT/CD40L-M in CD40+ NSCLC cells increased SA-beta-gal staining activity and inhibited DNA synthesis and cell proliferation.
T cell-stimulated CLL cells actively recruited monocytes, and CD40L was identified as the responsible T-cell factor that mediated recruitment.
this study shows that decreased serum levels of soluble CD40L correlate in treated patients with Relapsing-Remitting Multiple Sclerosis
In conclusion, we described a new pathway of platelet-monocyte interaction, mediated by sCD40L and oxidative stress that may contribute to the progression of endothelial dysfunction during Shiga toxin 2-associated hemolytic uremic syndrome.
show that sCD40L/alpha5beta1 interaction leads to platelet activation as evaluated in the human whole blood
In this first X chromosome-wide association study of adult patients with IBD, we identified an IBD susceptibility locus with genome-wide significance at rs2427870 on chrXq26.3, located 66 kbp upstream of CD40LG and 83.4 kbp upstream of ARHGEF6 [OR, 1.22; combined p = 3.79 x 10-15].
Study indicates that the rs1126535C/T polymorphism of CD154 gene was involved in the progression of Chinese SLE patients, probably by affecting the expression of CD154.
study found that plasma CD40L was associated with acute chest syndrome (ACS), and that sickle cell anemia (SCA)patients with a lifetime history of ACS (ACS+) presented significantly higher plasma CD40L and TSP-1 than patients who had never experienced ACS (ACS-)
this paper demonstrates importance of CD40/CD40L signaling on IL-10-producing regulatory B cells in Chinese children with Henoch-Schonlein purpura nephritis

Mouse (Murine) CD40 Ligand (CD40LG) Interaktionspartner

it is the combination of CD40L and the cytokines secreted by activated t-cells that licenses dendritic cellss and influences the effector class of the immune response
Deficiency of (hematopoietic) CD40L protects against dissecting aneurysm formation and reduces the incidence of fatal rupture. This is associated with a decreased accumulation and activation of inflammatory cells and a dampened protease activity in the arterial wall.
T-cell zone-specific TCRbeta repertoires revealed that CD154 deficiency shifts the distribution of Vbeta-Jbeta genes after antigen exposure
CD40L controls obesity-associated vascular inflammation, oxidative stress and endothelial dysfunction in mice and potentially humans.
These results suggest that combination of IL-21, anti-Tim1 and CD40L treatment induced B10 cell's IL-10 competency in vitro and inhibited periodontal bone loss in ligature-induced experimental periodontitis.
MR1-induced bone accrual was associated with increased Treg development and elevated production of cytotoxic T lymphocyte antigen 4, a costimulation inhibitor that promotes T cell anergy and CD8+ T cell expression of the bone anabolic ligand Wnt-10b.
These results suggest that CD40-activated CD40L reverse signalling has striking and opposite effects on the growth and elaboration of dendrites among major classes of brain neurons by PKC-dependent mechanisms.
Soluble CD40 ligand directly alters glomerular permeability and may act as a circulating permeability factor in focal segmental glomerulosclerosis.
studies identify a novel molecular mechanism of regulation of CD40L by the transcription factor GLI2 in the tumor microenvironment downstream of CCR3 signaling
our results unambiguously demonstrate that while CD40L is critical to generate effective primary CD8(+) T-cell responses also under inflammatory conditions, CD40L expression by CD8(+) T cells themselves is dispensable in acute lymphocytic choriomeningitis virus infection.
Platelets promote allergic asthma through the expression of CD154.
CD40L does not play a functional role in experimental acute pancreatitis
The tissue-specific, activation-dependent and reversible expression of CD40L fully mimics the physiological induction and disappearance of the molecule from the surface of murine T lymphocytes.
there is a major involvement of the CD40-CD40L signaling pathway in long-term brain dysfunction in an animal model of sepsis.
Report targeting and liposomal drug delivery of methotrexate to CD40L expressing T cells for treatment of autoimmune diseases.
although treated CD40 knockout mice remained healed, developed long-term immunity, and were resistant to secondary Leishmania major challenge, treated CD40L knockout reactivated their lesion after cessation of rIL-12 treatment.
PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development.
Anti-OX40L mAb could prolong secondary heart allograft survival based on CD40/CD40L and LFA-1/ICAM-1 blockade.
CD40 on lymph node fibroblasts facilitated bidirectional communication with CD4(+) T cells via CD40-CD40L, thereby altering fibroblast gene expression of immune regulatory molecules.
CD40L mediates neointima formation via its classic receptor CD40 rather than via its recently described novel interaction with Mac-1.

Pig (Porcine) CD40 Ligand (CD40LG) Interaktionspartner

CD40 ligand has a role in inducing endothelial dysfunction in human and porcine coronary artery endothelial cells

Cow (Bovine) CD40 Ligand (CD40LG) Interaktionspartner

Results demonstrated greater CD40 and CD40L expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.

Rhesus Monkey CD40 Ligand (CD40LG) Interaktionspartner

Both two-trimer and four-trimer forms of macaque CD40L were active in B-cell proliferation assays using macaque and human cells.

CD40 Ligand (CD40LG) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.

Alternative names and synonyms associated with CD40 Ligand (CD40LG)

CD40 ligand (CD40LG) Antikörper
CD40 ligand (cd40l) Antikörper
TNF superfamily member 5 (cd40l) Antikörper
CD40 ligand (Cd40lg) Antikörper

CD40-L Antikörper
Cd40l Antikörper
CD154 Antikörper
gp39 Antikörper
hCD40L Antikörper
HIGM1 Antikörper
IGM Antikörper
IMD3 Antikörper
Ly-62 Antikörper
Ly62 Antikörper
T-BAM Antikörper
Tnfsf5 Antikörper
TRAP Antikörper

Bezeichner auf Proteinebene für anti-CD40 Ligand (CD40LG) Antikörper

CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) , CD40 ligand , TNF superfamily member 5 , CD40 antigen ligand , CD40-L , T-B cell-activating molecule , T-cell antigen Gp39 , TNF-related activation protein , tumor necrosis factor (ligand) superfamily member 5 , tumor necrosis factor ligand superfamily member 5 , CD40 ligand CD154 , tumor necrosis factor (ligand) superfamily, member 5 , human : hyper-IgM syndrome , uncharacterized protein LOC100358388 , putative CD154 (CD40 ligand) , CD154 protein

GENE ID	SPEZIES
473802	Pan troglodytes
100286596	Salmo salar
100136698	Oncorhynchus mykiss
959	Homo sapiens
21947	Mus musculus
84349	Rattus norvegicus
397231	Sus scrofa
403468	Canis lupus familiaris
282387	Bos taurus
100358388	Oryctolagus cuniculus
100733664	Cavia porcellus
493850	Felis catus
395485	Gallus gallus
767628	Ovis aries
574160	Macaca mulatta

Ausgewählte Anbieter für anti-CD40 Ligand (CD40LG) Antikörper

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