Microtubule Star Antikörper (N-Term)
Dieses Anti-Microtubule Star-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Microtubule Star in IHC (p) und WB. Geeignet für Human, Maus und Ratte.
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Kurzübersicht für Microtubule Star Antikörper (N-Term) (ABIN3031776)
Target
Alle Microtubule Star (MTS) Produkte
Microtubule Star (MTS)
Reaktivität
Human, Maus, Ratte
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Bindungsspezifität
- N-Term
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Aufreinigung
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human, mouse and rat).
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Isotyp
- IgG
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Applikationshinweise
- Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The lyophilized PP2Ac antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
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- Microtubule Star (MTS)
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Andere Bezeichnung
- PP2Ac
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Hintergrund
- The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
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UniProt
- P67775
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Pathways
- PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
Target
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