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Mesothelin Proteine

(Mesothelin (MSLN))
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].

73 Treffer

MSLN Spezies: Maus Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN7013456
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN6938912
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN5674604
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6731265
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2444164
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN6731266
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN6253196
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6731264
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN5954923
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN5954924
 
MSLN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505150
 
MSLN Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN4371836
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504470
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504468
 
MSLN Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7583298
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504471
 
MSLN Spezies: Human Wirt: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
Produktnummer ABIN7535010
 
MSLN Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7580757
 
MSLN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7578271
 
MSLN Spezies: Maus Wirt: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, ELISA, Imm, AcA Active
Produktnummer ABIN7607601
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Flow Cytometry (FACS)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Phage Display (PhD)
    • Protein Interaction (PI)
    • Surface Plasmon Resonance (SPR)
    • Cryogenic electron microscopy (cryo-EM)
  • Reaktivität
    • Human
    • Mouse
    • Cynomolgus
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Human Cells
    • Cell-free protein synthesis (CFPS)
    • Yeast
    • Wheat germ
  • Bindungsspezifität
    • AA 296-580
    • AA 298-600
    • AA 1-375
    • AA 296-598
    • AA 296-600
    • AA 37-286
    • AA 406-690
    • C-Term
    • Transcript Variant 1
    • cleaved
    • AA 1-621
    • AA 24-202
    • AA 296-591
    • AA 296-606
    • AA 298-582
    • AA 302-359
    • AA 345-548
    • AA 36-600
    • AA 37-598
    • AA 400-615
    • AA 488-600
  • Konjugat
    • His tag
    • Fc Tag
    • Unkonjugiert
    • His tag,Biotin
    • Fc Tag,FITC
    • His tag,AVI tag,Biotin
    • His tag,GST tag
    • His-Avi Tag,Biotin
    • Strep Tag
    • APC,His tag
    • Alexa Fluor 488,His tag
    • Alexa Fluor 555,His tag
    • Alexa Fluor 647,His tag
    • Biotin,His-Avi Tag
    • DYKDDDDK Tag,Strep Tag
    • FITC,Fc Tag
    • FITC,His tag
    • FITC,His-Avi Tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,Biotin
    • Fc Tag,His tag
    • Fc-Avi Tag,Biotin
    • GFP tag,His tag
    • GST tag
    • His tag,AVI tag
    • His tag,FITC
    • His tag,RFP tag
    • His-Avi Tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • PE,His tag
    • PE,His-Avi Tag
    • mFc-His Tag
  • Protein-Typ
    • Recombinant
    • Synthetic Nanodisc
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • custom-made
    • MALS verified
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • BioLegend
    • OriGene
    • Signalway
    • CUSABIO
    • Cohesion Biosciences
    • RayBiotech

Aktuelle Publikationen für unsere Mesothelin Proteine

Li, Li, Xu, Xing, Ding, Jing, Wang, Hong: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).

Sirois, Deny, Li, Fall, Moore: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).

Sirois, Deny, Baierl, George, Moore: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).

Chang, Chen, Chen, Chiang, Chen, Mao, Lin, Lin Chiang, Cheng: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).

Li, Bharadwaj, Zhang, Zhang, Mu, Fisher, Brunicardi, Chen, Yao: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." in: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).

Aliase für Mesothelin Proteine

mesothelin (MSLN) Proteine
mesothelin (Msln) Proteine
mesothelin (LOC611363) Proteine
mesothelin (LOC100524016) Proteine
MPF Proteine
MSLN Proteine
SMRP Proteine
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