MCAM Proteins

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Aktuelle Publikationen für unsere MCAM Proteine

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Luo, Duan, Qian, Feng, Wu, Wang, Feng, Yang, Qin, Yan: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." in: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).

Tu, Zhang, Yan, Luo, Kong, Wen, Ye, Chen, Feng, Liu, Wu, Yan: "CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development." in: Cell research, Vol. 25, Issue 3, pp. 275-87, (2015) (PubMed).

Keller, Kalt, Raab, Schachner, Mayrhofer, Kerjaschki, Hantusch: "Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127169, (2015) (PubMed).

Ishikawa, Wondimu, Oikawa, Ingerpuu, Virtanen, Patarroyo: "Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 36, pp. 5-14, (2014) (PubMed).

Ye, Zhang, Tu, Sun, Liu, Lu, Feng, Yang, Liu, Yan: "Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension." in: Nature communications, Vol. 4, pp. 2803, (2013) (PubMed).

Simon, Martin, Smith, Thaikoottathil, Bowler, Barenkamp, Chu: "Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence." in: American journal of respiratory cell and molecular biology, Vol. 44, Issue 5, pp. 606-13, (2011) (PubMed).

Aliase für MCAM Proteine

melanoma cell adhesion molecule (MCAM) Proteine
melanoma cell adhesion molecule (Mcam) Proteine
melanoma cell adhesion molecule b (mcamb) Proteine
1-gicerin Proteine
AV025631 Proteine
CD146 Proteine
cd146 Proteine
CD149 Proteine
gicerin Proteine
id:ibd3512 Proteine
mcam Proteine
MCAM Proteine
MUC18 Proteine
Muc18 Proteine
s-endo Proteine
s-gicerin Proteine

MCAM Proteine

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Aktuelle Publikationen für unsere MCAM Proteine

Aliase für MCAM Proteine

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