anti-RAF1 (RAF1) Antikörper

Bezeichnung:: anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 Antikörper (RAF1)

Auf www.antikoerper-online.de finden Sie aktuell 904 V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Antikörper von 33 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAF1 Kits (20) und RAF1 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 985 RAF1 Produkte verfügbar.

Synonyme:: 6430402F14Rik, AA990557, Afr-1, Afr1, BB129353, c-raf, cRaf, Craf1, D830050J10Rik, mKIAA0854, NS5, raf, Raf-1, RAF1, v-Raf

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	RAF1	5894	P04049
	RAF1	24703	P11345
	RAF1	387609	Q8C0C0
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-RAF1 Antikörper

Human RAF1 Primary Antibody für IHC - ABIN966940 : Gabriel, Bravery, Dougherty, Kayley, Malster, Scales: Vascular access: indications and implications for patient care. in Nursing standard (Royal College of Nursing (Great Britain) : 1987) 2005 (PubMed)
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Human Polyclonal RAF1 Primary Antibody für DB, ELISA - ABIN4369727 : Gohlke, Kuhn, Case: Change in protein flexibility upon complex formation: analysis of Ras-Raf using molecular dynamics and a molecular framework approach. in Proteins 2004 (PubMed)
Show all 3 Pubmed References
Human Monoclonal RAF1 Primary Antibody für FACS, IHC - ABIN969560 : Takezawa, Okamoto, Yonesaka, Hatashita, Yamada, Fukuoka, Nakagawa: Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells. in Cancer research 2009 (PubMed)
Show all 2 Pubmed References
Human Monoclonal RAF1 Primary Antibody für FACS, IHC - ABIN969559 : Hofmann, Heinrich, Radziwill, Radziwil, Moelling: A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells. in Molecular cancer research : MCR 2009 (PubMed)
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Human Polyclonal RAF1 Primary Antibody für ELISA, ICC - ABIN6260344 : Cui, Lin, Shi, Pan: Hypoxic postconditioning attenuates apoptosis via inactivation of adenosine A2a receptor through NDRG3-Raf-ERK pathway. in Biochemical and biophysical research communications 2017 (PubMed)
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Human Polyclonal RAF1 Primary Antibody für ELISA, ICC - ABIN6255230 : Wu, Zhu, Yin, Kang, Cao, Tian, Zhang, Lu, Liu: Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer. in Cancer medicine 2018 (PubMed)
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Human Monoclonal RAF1 Primary Antibody für WB - ABIN260776 : Chiloeches, Mason, Marais: S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3. in Molecular and cellular biology 2001 (PubMed)
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Virus Polyclonal RAF1 Primary Antibody für ICC, IF - ABIN4340713 : Retallack, Di Lullo, Arias, Knopp, Laurie, Sandoval-Espinosa, Mancia Leon, Krencik, Ullian, Spatazza, Pollen, Mandel-Brehm, Nowakowski, Kriegstein, DeRisi: Zika virus cell tropism in the developing human brain and inhibition by azithromycin. in Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
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Human Polyclonal RAF1 Primary Antibody für IP, IHC - ABIN222938 : Ito, Nagayasu, Okumura-Noji, Lu, Nishida, Miura, Asai, Kheirollah, Nakaya, Yokoyama: Mechanism for FGF-1 to regulate biogenesis of apoE-HDL in astrocytes. in Journal of lipid research 2007 (PubMed)
Human Polyclonal RAF1 Primary Antibody für DB - ABIN389828 : Duan, Cobb: Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

Weitere Antikörper gegen RAF1 Interaktionspartner

Human V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

Data indicate that Raf-1 proto-oncogene (zeige RAB1A Antikörper), serine-threonine kinase (zeige TLK2 Antikörper) (RAF1) is a negative regulator of hepatocarcinogenesis.
we report a patient with an inherited RAF1-associated Noonan syndrome, presenting with an antenatally diagnosed abnormality of skull shape, bilateral subdural haematomas, of unknown cause, delayed myelination and polymicrogyria.
Raf1 may serve as a novel prognostic factor and potential target for improving the longterm outcome of nonsmall cell lung cancer (NSCLC).
Results provide evidence that RAF1 binding to SPRY4 (zeige SPRY4 Antikörper) is regulated by miR (zeige MLXIP Antikörper)-1908 in glioma tumors.
High RAF1 expression is associated with malignant melanoma.
two premature neonates with progressive biventricular hypertrophy found to have RAF1 variants in the CR2 domain, are reported.
Data indicate connector enhancer of kinase suppressor of Ras 1 (zeige CNKSR1 Antikörper) protein (CNK1 (zeige CNKSR1 Antikörper)) as a molecular platform that controls c-raf protein (RAF) and c-akt (zeige AKT1 Antikörper) protein (AKT (zeige AKT1 Antikörper)) signalling and determines cell fate decisions in a cell type- and cell stage-dependent manner.
CRAF is a bona fide alternative oncogene (zeige RAB1A Antikörper) for BRAF (zeige BRAF Antikörper)/NRAS (zeige NRAS Antikörper)/GNAQ (zeige GNAQ Antikörper)/GNA11 (zeige GNA11 Antikörper) wild type melanomas
Authors evaluated the expression of known targets of miR (zeige MLXIP Antikörper)-125a and found that sirtuin-7 (zeige SIRT7 Antikörper), matrix metalloproteinase-11 (zeige MMP11 Antikörper), and c-Raf were up-regulated in tumor tissue by 2.2-, 3-, and 1.7-fold, respectively. Overall, these data support a tumor suppressor role for miR (zeige MLXIP Antikörper)-125a.
Overexpression of ciRS-7 in HCT116 and HT29 cells led to the blocking of miR-7 (zeige LILRB1 Antikörper) and resulted in a more aggressive oncogenic phenotype, and ciRS-7 overexpression permitted the inhibition of miR-7 (zeige LILRB1 Antikörper) and subsequent activation of EGFR (zeige EGFR Antikörper) and RAF1 oncogenes

Zebrafish V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

cdk10 (zeige CDK10 Antikörper) has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a expression
Our results indicate that Rb-Raf-1 interaction plays an important role in spontaneous hair cell regeneration in zebrafish
Zebrafish embryos with morpholino knockdown of raf1 demonstrated the need for raf1 for the development of normal myocardial structure and function.
analysis of the roles of Raf- and PI3K-signalling pathways in melanoma

Cow (Bovine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

data suggest that G alpha(i3), Shc (zeige SHC1 Antikörper), Grb2 (zeige GRB2 Antikörper), Ras, and Raf-1 link Src (zeige SRC Antikörper) to activation of MAPK (zeige MAPK1 Antikörper) and to the AT(2)-dependent increase in eNOS (zeige NOS3 Antikörper) expression in PAECs

Mouse (Murine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

Data indicate that Raf-1 proto-oncogene (zeige RAB1A Antikörper), serine-threonine kinase (zeige CDK4 Antikörper) (RAF1) is a negative regulator of hepatocarcinogenesis.
Results indicate that proto-oncogene c-RAF (CRAF) function affects postmitotic neural cell differentiation and points to a critical role of CRAF-dependent growth factor signaling pathway in the postmitotic development of adult-born neurons.
our studies demonstrate that PDE8A (zeige PDE8A Antikörper) inhibition by enzymatic inhibitors or PDE8A (zeige PDE8A Antikörper)-Raf-1 kinase complex disruptors decreases Teff cell adhesion and migration under flow, and represents a novel approach to target T cells in inflammation
BRAF (zeige BRAF Antikörper) and ROKalpha (zeige ROCK2 Antikörper) form independent RAF1 complexes in embryonic fibroblasts (MEFs) treated with epidermal growth factor (EGF (zeige EGF Antikörper)).
Mechanistically, BRAF (zeige BRAF Antikörper) and RAF1 operate independently to balance MAPK (zeige MAPK1 Antikörper) signaling: BRAF (zeige BRAF Antikörper) promotes ERK (zeige EPHB2 Antikörper) activation, while RAF1 dims stress kinase activation.
Neuroprotective (arylthio)cyclopentenone prostaglandins directly bind to c-Raf protein and protect cells from down-regulation of the c-Raf protein itself, resulting in protection against oxidative stress.
Additional Cyp (zeige PPIG Antikörper) genes are disregulated in the absence of Zhx2 (zeige ZHX2 Antikörper).
Zhx2 (zeige ZHX2 Antikörper) is a novel regulator of Mup expression; Zhx2 (zeige ZHX2 Antikörper) activates as well as represses expression of target genes
A- and B-Raf (zeige SNRPE Antikörper) ablation in chondrocytes does not alter skeletal development, whereas ablation of C-Raf decreases hypertrophic chondrocyte apoptosis and impairs vascularization of the growth plate. However, ablation of C-Raf does not impair phosphate-induced ERK1/2 phosphorylation in vitro, but leads to rickets by decreasing VEGF (zeige VEGFA Antikörper) protein stability.
We confirmed that Raf1(L613V) knock-in confers a NS-like phenotype, including cardiac hypertrophy. Active RSK3 (zeige RPS6KA2 Antikörper) was increased in Raf1(L613V) mice. Constitutive RSK3 (zeige RPS6KA2 Antikörper) gene deletion prevented the Raf1(L613V)-dependent concentric growth in width of the cardiac myocyte and attenuated cardiac hypertrophy in female mice.

Xenopus laevis V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

Both c-Raf and B-Raf (zeige BRAF Antikörper) are required for Ras-induced MEK1 (zeige MAP2K1 Antikörper) and p42 (zeige EPB42 Antikörper) MAP kinase (zeige MAPK1 Antikörper) activation.

RAF1 Antigen-Profil

Beschreibung des Gens

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Alternative names and synonyms associated with RAF1

Raf-1 proto-oncogene, serine/threonine kinase (RAF1) Antikörper
Raf-1 proto-oncogene, serine/threonine kinase (Raf1) Antikörper
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) Antikörper
Raf-1 proto-oncogene, serine/threonine kinase (raf1) Antikörper
zinc fingers and homeoboxes 2 (Zhx2) Antikörper
v-raf-leukemia viral oncogene 1 (Raf1) Antikörper
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) Antikörper

6430402F14Rik Antikörper
AA990557 Antikörper
Afr-1 Antikörper
Afr1 Antikörper
BB129353 Antikörper
c-raf Antikörper
cRaf Antikörper
Craf1 Antikörper
D830050J10Rik Antikörper
mKIAA0854 Antikörper
NS5 Antikörper
raf Antikörper
Raf-1 Antikörper
RAF1 Antikörper
v-Raf Antikörper

Bezeichner auf Proteinebene für RAF1

, , , , , , , , , , , , , , , , , , , , , , , , , , , Oncogene RAF1 RAF proto-oncogene serine/threonine-protein kinase proto-oncogene c-RAF raf proto-oncogene serine/threonine protein kinase C-RAF cRaf murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV) raf-1 v-raf-1 murine leukemia viral oncogene homolog 1 murine leukemia viral oncogene homolog serine/threonine protein kinase RAF1 MIL proto-oncogene serine/threonine-protein kinase RAF-1 c-mil protein murine leukemia viral (v-raf-1) oncogene homolog 1 RAF proto-oncogene serine/threonine-protein kinase-like AFP regulator 1 alpha fetoprotein regulation 1, adult alpha-fetoprotein regulator 1 regulator of AFP zinc finger and homeodomain protein 2 zinc fingers and homeoboxes protein 2 Craf1 transforming murine sarcoma 3611 oncogene 1 sarcoma 3611 oncogene v-raf-1 leukemia viral oncogene 1 Proto-oncogene c-RAF Raf-1

GENE ID	SPEZIES
5894	Homo sapiens
24703	Rattus norvegicus
30716	Danio rerio
396245	Gallus gallus
460182	Pan troglodytes
484648	Canis lupus familiaris
521196	Bos taurus
549871	Xenopus (Silurana) tropicalis
694725	Macaca mulatta
100173732	Pongo abelii
100347407	Oryctolagus cuniculus
100415300	Callithrix jacchus
100482255	Ailuropoda melanoleuca
387609	Mus musculus
100582599	Nomascus leucogenys
110157	Mus musculus
397857	Xenopus laevis
107131151	Bos taurus
100720110	Cavia porcellus

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