anti-MAP3K5 (MAP3K5) Antikörper

Bezeichnung:: anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 Antikörper (MAP3K5)

Auf www.antikoerper-online.de finden Sie aktuell 415 Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antikörper von 33 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K5 Kits (44) und MAP3K5 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 500 MAP3K5 Produkte verfügbar.

Synonyme:: 7420452D20Rik, ASK, Ask1, MAPKKK5, Mekk5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11, RGD1306565

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	MAP3K5	4217	Q99683
	MAP3K5	26408	O35099
	MAP3K5	365057
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human MAP3K5 Antikörper:

anti-Mouse (Murine) MAP3K5 Antikörper:

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Verknüpfte Pathways mit anti-MAP3K5 Antikörper

Unfolded protein response

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Am meisten referenzierte anti-MAP3K5 Antikörper

Human MAP3K5 Primary Antibody für IHC - ABIN965599 : Zhang, Zheng, Storz, Min: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. in The Journal of biological chemistry 2005 (PubMed)
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Human Polyclonal MAP3K5 Primary Antibody für IHC - ABIN965600 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. in The Journal of biological chemistry 2003 (PubMed)
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Human Polyclonal MAP3K5 Primary Antibody für IHC - ABIN965601 : Goldman, Chen, Fu: Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. in The Journal of biological chemistry 2004 (PubMed)
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Human Monoclonal MAP3K5 Primary Antibody für FACS, IF - ABIN966515 : Woolcott, SenGupta, Hanna, Aronson: Estrogen and progesterone receptor levels in nonneoplastic breast epithelium of breast cancer cases versus benign breast biopsy controls. in BMC cancer 2008 (PubMed)
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Human MAP3K5 Primary Antibody für IHC - ABIN965598 : Mabuchi, Ohmichi, Kimura, Nishio, Arimoto-Ishida, Yada-Hashimoto, Tasaka, Murata: Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. in Endocrinology 2003 (PubMed)
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Human Polyclonal MAP3K5 Primary Antibody für IHC, WB - ABIN362194 : Kim, Khursigara, Sun, Franke, Chao: Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. in Molecular and cellular biology 2001 (PubMed)
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Human Polyclonal MAP3K5 Primary Antibody für ELISA, WB - ABIN2477506 : Bhuta, Prathikanti: Colitis cystica profunda. in Southern medical journal 1976 (PubMed)
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Human Monoclonal MAP3K5 Primary Antibody für ICC, FACS - ABIN969273 : Widenmaier, Ao, Kim, Warnock, McIntosh et al.: Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent ... in The Journal of biological chemistry 2009 (PubMed)
Human Polyclonal MAP3K5 Primary Antibody für IF (p), IHC (p) - ABIN683128 : Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity. in Pancreas 2015 (PubMed)
Human Polyclonal MAP3K5 Primary Antibody für ELISA, WB - ABIN561803 : Nectoux, Fichou, Cagnard, Bahi-Buisson, Nusbaum, Letourneur, Chelly, Bienvenu: Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy. in Journal of molecular medicine (Berlin, Germany) 2011 (PubMed)

Weitere Antikörper gegen MAP3K5 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

Knockdown of miR (zeige MLXIP Antikörper)-20a enhanced sensitivity of colorectal cancer cells to cisplatin through the ROS (zeige ROS1 Antikörper)/ASK1/JNK (zeige MAPK8 Antikörper) pathway.
Findings offer insight into positive regulation of Akt (zeige AKT1 Antikörper) signaling through P2Y12 (zeige P2RY12 Antikörper) phosphorylation as well as MAPK (zeige MAPK1 Antikörper) signaling in platelets by ASK1.
Cold stress-induced ferroptosis involves the ASK1-p38 (zeige CRK Antikörper) pathway.
TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1 (zeige PRMT1 Antikörper)
These findings indicate that chaetocin arrests the cell cycle and induces apoptosis by regulating the reactive oxygen species-mediated ASK-1/JNK (zeige MAPK8 Antikörper) signaling pathways.
Findings provide evidence that ASK-1 expression is regulated by SLC35F2 (zeige SLC35F2 Antikörper) which exerts its oncogenic effect on papillary thyroid carcinoma progression through activation of TGFBR-1 (zeige TGFBR1 Antikörper) and ASK-1.
Co-administration of acetaminophen and 5'-AMP (zeige APRT Antikörper) significantly ameliorated APAP-induced hepatotoxicity in mice. This was triggered by attenuating apoptosis signal-regulated kinase 1(ASK1) methylation and increasing ubiquitination-mediated ASK1 protein degradation.
The anti-cancer mechanism for the AgNPs may be involved in activating the ASK1-JNK (zeige MAPK8 Antikörper)/p38 (zeige CRK Antikörper)-Caspase-3 (zeige CASP3 Antikörper) pathway.
TRAF1 (zeige TRAF1 Antikörper) functions as a positive regulator of insulin (zeige INS Antikörper) resistance, inflammation, and hepatic steatosis dependent on the activation of ASK1-P38 (zeige CRK Antikörper)/JNK (zeige MAPK8 Antikörper) axis.
LRRK2-induced apoptosis was suppressed by ASK1 inhibition in neuronal stem cells derived from patients with Parkinson's disease (PD). These results clearly indicate that LRRK2 acts as an upstream kinase in the ASK1 pathway and plays an important role in the pathogenesis of PD

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

PBL27 interacts with both CERK1 and the MAPK (zeige MAPK1 Antikörper) kinase kinase MAPKKK5 at the plasma membrane and knockout of MAPKKK5 compromise chitin-induced MAPK (zeige MAPK1 Antikörper) kinase activation and disease resistance to Alternaria brassicicola.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

Findings offer insight into positive regulation of Akt (zeige AKT1 Antikörper) signaling through P2Y12 (zeige P2RY12 Antikörper) phosphorylation as well as MAPK (zeige MAPK1 Antikörper) signaling in platelets by ASK1.
This study demonstrated that the first evidence suggesting that ASK1 may play some role in the pathophysiology of Alzheimer's Disease and brain aging.
Oxidative and endoplasmic reticulum stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury.
The results of this investigation indicate ASK1 inhibition prolongs keratinocyte and blastemal cell activation leading to ear regeneration.
These results suggest that the platelet Ask1 plays an important role in regulation of hemostasis and thrombosis.
Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.
These results demonstrate that trans-fatty acids promote extracellular ATP-induced apoptosis by targeting ASK1 and indicate novel TFA (zeige F3 Antikörper)-associated pathways leading to inflammatory signal transduction and cell death that underlie the pathogenesis and progression of trans-fatty acids-induced atherosclerosis.
Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (zeige AKT1 Antikörper)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (zeige AKT1 Antikörper) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.
ASK1 MAP kinase (zeige MAPK1 Antikörper) signaling cascade is an important regulator of chondrocyte terminal differentiation.
ASK1 mediates astrocyte activation and leads to glial scar formation after cerebral ischaemia.

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

PP2A (zeige PPP2R2B Antikörper) and AIP1 (zeige PDCD6IP Antikörper) cooperatively induce activation of ASK1-JNK (zeige MAPK8 Antikörper) signaling and vascular endothelial cell apoptosis.
These results indicate an important regulatory role of ASK1 in porcine circovirus type 2-induced apoptotic responses.
MAP3K5 is expressed in the heart, liver, spleen, lung, kidney, muscle, fat, pancrea, ileum, and stomach tissues of pigs.

MAP3K5 Antigen-Profil

Beschreibung des Gens

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK.

Alternative names and synonyms associated with MAP3K5

mitogen-activated protein kinase kinase kinase 5 (MAP3K5) Antikörper
mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) Antikörper
mitogen-activated protein kinase kinase kinase 5 (Map3k5) Antikörper
mitogen-activated protein kinase kinase kinase 5 (map3k5) Antikörper

7420452D20Rik Antikörper
ASK Antikörper
Ask1 Antikörper
MAPKKK5 Antikörper
Mekk5 Antikörper
mitogen-activated protein kinase kinase kinase 5 Antikörper
MUD21.11 Antikörper
MUD21_11 Antikörper
RGD1306565 Antikörper

Bezeichner auf Proteinebene für MAP3K5

ASK-1 , MAP/ERK kinase kinase 5 , MAPK/ERK kinase kinase 5 , MEK kinase 5 , MEKK 5 , apoptosis signal regulating kinase 1 , apoptosis signal-regulating kinase 1 , mitogen activated protein kinase kinase kinase 5 , mitogen-activated protein kinase kinase kinase 5 , mitogen-activated protein kinase kinase kinase 5 pseudogene

GENE ID	SPEZIES
4217	Homo sapiens
836819	Arabidopsis thaliana
26408	Mus musculus
537380	Bos taurus
365057	Rattus norvegicus
555703	Danio rerio
100622769	Sus scrofa

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