Protein Überblick

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Alternative names and synonyms associated with MAP2K3

• mitogen-activated protein kinase kinase 3 (MAP2K3) Antikörper
• mitogen-activated protein kinase kinase 3 (Map2k3) Antikörper
• mitogen activated protein kinase kinase 3 (Map2k3) Antikörper
• MAP kinase activator XMEK3 (map2k3) Antikörper

• AW212142 Antikörper
• MAPKK3 Antikörper
• MEK3 Antikörper
• Mkk3 Antikörper
• mMKK3b Antikörper
• Alle Synonyme
• Prkmk3 Antikörper
• SAPKK-2 Antikörper
• SAPKK2 Antikörper

Bezeichner auf Proteinebene für MAP2K3

MAP kinase kinase 3 , MAPK/ERK kinase 3 , MAPKK 3 , MEK 3 , SAPK kinase 2 , dual specificity mitogen-activated protein kinase kinase 3 , stress-activated protein kinase kinase 2 , mitogen activated protein kinase kinase 3 , protein kinase, mitogen-activated, kinase 3