anti-BICD2 (BICD2) Antikörper

Bezeichnung:: anti-Bicaudal D Homolog 2 (Drosophila) Antikörper (BICD2)

Auf www.antikoerper-online.de finden Sie aktuell 64 Bicaudal D Homolog 2 (Drosophila) (BICD2) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 72 BICD2 Produkte verfügbar.

Synonyme:: 0610027D24Rik, 1110005D12Rik, AA408834, bA526D8.1, bicd2, MGC84972, mKIAA0699, SMALED2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	BICD2	23299	Q8TD16
	BICD2	76895	Q921C5
	BICD2	306809
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-BICD2 (BICD2) Antikörper

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anti-Human BICD2 Antikörper:

anti-Mouse (Murine) BICD2 Antikörper:

anti-Rat (Rattus) BICD2 Antikörper:

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Verknüpfte Pathways mit anti-BICD2 Antikörper

Maintenance of Protein Location

Am meisten referenzierte anti-BICD2 Antikörper

Human Polyclonal BICD2 Primary Antibody für IHC, IHC (p) - ABIN4284611 : Terenzio, Golding, Russell, Wicher, Rosewell, Spencer-Dene, Ish-Horowicz, Schiavo: Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. in The EMBO journal 2014 (PubMed)

Weitere Antikörper gegen BICD2 Interaktionspartner

Human Bicaudal D Homolog 2 (Drosophila) (BICD2) Interaktionspartner

BICD2 facilitates infection by promoting the trafficking of viral cores to the nucleus, thereby promoting nuclear entry of the viral genome and infection
BICD2 missense mutations were identified in patients with severe muscular atrophy with arthrogryposis and asymptomatic individuals with subclinical features.
Data suggest that BICD1 (zeige BICD1 Antikörper) and BICD2 are highly expressed in the nervous system during development and are important in neuronal homeostasis. [REVIEW]
results reveal that dominant mutations in BICD2 hyperactivate DDB motility and suggest that an imbalance of minus versus plus end-directed microtubule motility in neurons may underlie spinal muscular atrophy.
These findings give further insight into the clinical and pathoanatomical consequences of BICD2 mutations.
several analyses of vesicular transport demonstrated that Rab6A (zeige RAB6A Antikörper) and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells
the features of BICD2 spinal muscular atrophy, lower extremity predominant are consistent with a pathological process that preferentially affects lumbar lower motor neurons
Mutations in BICD2 cause congenital autosomal-dominant spinal muscular atrophy and massive Golgi fragmentation in affected cells.
BICD2 mutations cause non-5q linked spinal muscular atrophy in humans
Disease causing mutations resulting in amino acid substitutions in two binding regions of BICD2 increase its binding affinity for the cytoplasmic dynein (zeige DYNC1H1 Antikörper)-dynactin (zeige DCTN1 Antikörper) complex.

Mouse (Murine) Bicaudal D Homolog 2 (Drosophila) (BICD2) Interaktionspartner

Data suggest that binding of Lis1 (zeige PAFAH1B1 Antikörper) to DDB complex does not strongly disrupt processive motility along microtubules; motile DDB complex binds up to two Lis1 (zeige PAFAH1B1 Antikörper) dimers; mutational analysis suggested that Lis1 (zeige PAFAH1B1 Antikörper) binds directly to the dynein motor domains during DDB complex movement. (Lis1 (zeige PAFAH1B1 Antikörper) = lissencephaly 1 protein (zeige PAFAH1B1 Antikörper); DDB complex = dynein-dynactin (zeige DCTN1 Antikörper)-BicD2 complex; BicD2 = bicaudal D homolog 2 protein)
several analyses of vesicular transport demonstrated that Rab6A (zeige RAB6A Antikörper) and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells
Data indicate that Bicaudal-D2 (BICD2)-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration.
LIS1 (zeige PAFAH1B1 Antikörper) is required for dynein-mediated transport induced by membrane tethering of BICD2-N and LIS1 (zeige PAFAH1B1 Antikörper) contributes to dynein accumulation at microtubule plus ends and BICD2-positive cellular structures.
BICD2-N transgene increased lifespan in 'low copy' SOD1-G93A ALS transgenic mice.

BICD2 Antigen-Profil

Beschreibung des Gens

This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.

Alternative names and synonyms associated with BICD2

BICD cargo adaptor 2 (BICD2) Antikörper
bicaudal D homolog 2 (Drosophila) (Bicd2) Antikörper
BICD cargo adaptor 2 (Bicd2) Antikörper
BICD cargo adaptor 2 L homeolog (bicd2.L) Antikörper
BICD cargo adaptor 2 (bicd2) Antikörper
zgc:171572 (zgc:171572) Antikörper

0610027D24Rik Antikörper
1110005D12Rik Antikörper
AA408834 Antikörper
bA526D8.1 Antikörper
bicd2 Antikörper
MGC84972 Antikörper
mKIAA0699 Antikörper
SMALED2 Antikörper

Bezeichner auf Proteinebene für BICD2

bic-D 2 , coiled-coil protein BICD2 , cytoskeleton-like bicaudal D protein homolog 2 , homolog of Drosophila bicaudal D , protein bicaudal D homolog 2 , bicaudal D homolog 2 , bicaudal D protein , bicaudal D homolog 2 (Drosophila) , protein bicaudal D homolog 2-like

GENE ID	SPEZIES
23299	Homo sapiens
76895	Mus musculus
306809	Rattus norvegicus
734304	Xenopus laevis
100327237	Xenopus (Silurana) tropicalis
100351714	Oryctolagus cuniculus
282447	Bos taurus
415990	Gallus gallus
465233	Pan troglodytes
484214	Canis lupus familiaris
562424	Danio rerio
706621	Macaca mulatta
100014670	Monodelphis domestica
100056101	Equus caballus
100227228	Taeniopygia guttata
100472389	Ailuropoda melanoleuca
100490789	Xenopus (Silurana) tropicalis
100447092	Pongo abelii
100512597	Sus scrofa
100545283	Meleagris gallopavo
100555618	Anolis carolinensis
100727856	Cavia porcellus

Ausgewählte Anbieter für anti-BICD2 (BICD2) Antikörper

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Show all anti-Bicaudal D Homolog 2 (Drosophila) (BICD2) Antikörper with Pubmed References

Human Bicaudal D Homolog 2 (Drosophila) (BICD2) Interaktionspartner

Mouse (Murine) Bicaudal D Homolog 2 (Drosophila) (BICD2) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with BICD2

Bezeichner auf Proteinebene für BICD2