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Low Density Lipoprotein Receptor Proteine

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].

32 Treffer

LDLR Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275138
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275139
 
LDLR Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Produktnummer ABIN1309277
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275140
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN2181455
 
LDLR Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN5526601
 
LDLR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Produktnummer ABIN7123785
 
LDLR Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Produktnummer ABIN7320327
 
LDLR Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1780661
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7491325
 
LDLR Spezies: Kaninchen Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN7013410
 
LDLR Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Produktnummer ABIN2870752
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant >80 % as determined by SDS-PAGE. Active
Produktnummer ABIN5954921
 
LDLR Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505399
 
LDLR Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505737
 
LDLR Spezies: Human Wirt: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7317949
 
LDLR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7577920
 
LDLR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7577919
 
LDLR Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Produktnummer ABIN7411576
 
LDLR Spezies: Human Wirt: Mammalian Cells Recombinant WB, SDS, ELISA
Produktnummer ABIN7577918
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rabbit
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Wheat germ
    • Human Cells
    • Yeast
  • Bindungsspezifität
    • AA 22-788
    • partial
    • AA 263-509
    • AA 1-790
    • AA 1-860
    • AA 105-205
    • AA 22-790
    • AA 22-807
    • AA 25-186
    • AA 335-588
    • AA 455-607
    • AA 497-742
    • AA 9-765
  • Konjugat
    • His tag
    • Fc Tag
    • GST tag
    • His tag,AVI tag
    • His tag,AVI tag,Biotin
    • His tag,GST tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • MALS verified
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • CUSABIO
    • OriGene

Aktuelle Publikationen für unsere Low Density Lipoprotein Receptor Proteine

Basak, Verghese, Yoon, Kim, Holtzman: "Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of A? uptake and degradation by astrocytes." in: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 13959-71, (2012) (PubMed).

Prunotto, Carnevali, Candiano, Murtas, Bruschi, Corradini, Trivelli, Magnasco, Petretto, Santucci, Mattei, Gatti, Scolari, Kador, Allegri, Ghiggeri: "Autoimmunity in membranous nephropathy targets aldose reductase and SOD2." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 507-19, (2010) (PubMed).

Aliase für Low Density Lipoprotein Receptor Proteine

low density lipoprotein receptor (LDLR) Proteine
low density lipoprotein receptor (Ldlr) Proteine
low density lipoprotein receptor a (ldlra) Proteine
low density lipoprotein receptor S homeolog (ldlr.S) Proteine
low density lipoprotein receptor L homeolog (ldlr.L) Proteine
FH Proteine
FHC Proteine
fhc Proteine
Hlb301 Proteine
LDLA Proteine
LDLCQ2 Proteine
ldlcq2 Proteine
ldlr Proteine
ldlr-a Proteine
ldlr-b Proteine
ldlr2-a Proteine
LDLRA Proteine
LDL receptor-2 Proteine
LDL receptor 1 Proteine
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