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LMO2 Produkte

(LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Kategorien

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008].

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Ausgewählte LMO2 Kategorien

LMO2 Antikörper

High quality antibodies with extensive validation data.

LMO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

LMO2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene LMO2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN1098128
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, StM
Validierungen
  • (5)
Kat. Nr. ABIN6939966
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, IF
Validierungen
  • (3)
Kat. Nr. ABIN6939968
Menge 100 μg
Datenblatt Datenblatt

Empfohlene LMO2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1155675
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1155676
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method
Validierungen
Kat. Nr. ABIN1155674
Menge 96 tests
Datenblatt Datenblatt

Empfohlene LMO2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1309514
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3087066
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3133442
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren LMO2 Produkten

Cheng, Ang, A El Farran, Li, Fang, Liu, Kong, Chin, Ling, Lim, Li, Huber, Loh, Loh, Lim: "Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors." in: Nature communications, Vol. 7, pp. 13396, (2018) (PubMed).

Stanulovic, Cauchy, Assi, Hoogenkamp: "LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage." in: Nucleic acids research, Vol. 45, Issue 17, pp. 9874-9888, (2017) (PubMed).

Sewell, Tanaka, El Omari, Mancini, Cruz, Fernandez-Fuentes, Chambers, Rabbitts: "Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex." in: Scientific reports, Vol. 4, pp. 3643, (2014) (PubMed).

Treanor, Zhou, Janke, Churchman, Ma, Lu, Chen, Mullighan, Sorrentino: "Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential." in: The Journal of experimental medicine, Vol. 211, Issue 4, pp. 701-13, (2014) (PubMed).

Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

Hirose, Inukai, Kikuchi, Furukawa, Ikawa, Kawamoto, Oram, G��ttgens, Kiyokawa, Miyagawa, Okita, Akahane, Zhang, Kuroda, Honna, Kagami, Goi, Kurosawa, Look, Matsui, Inaba, Sugita: "Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19)." in: Blood, Vol. 116, Issue 6, pp. 962-70, (2010) (PubMed).

Ryu, Evans-Galea, Gray, Bodine, Persons, Nienhuis: "An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation." in: Blood, Vol. 111, Issue 4, pp. 1866-75, (2008) (PubMed).

Natkunam, Zhao, Mason, Chen, Taidi, Jones, Hammer, Hamilton Dutoit, Lossos, Levy: "The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas." in: Blood, Vol. 109, Issue 4, pp. 1636-42, (2007) (PubMed).

Nakayama, Nakayama, Davidson, Sheu, Jinawath, Santillan, Salani, Bristow, Morin, Kurman, Wang, Shih: "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18739-44, (2006) (PubMed).

Synonyme und alternative Namen zu LMO2

LIM domain only 2 (lmo2), LIM domain only 2 (LMO2), LIM domain only 2 (Lmo2), LIM domain only 2 (rhombotin-like 1) (lmo2), LIM domain only 2 S homeolog (lmo2.S), LMO-2, lmo2-A, Rbtn-2, Rbtn2, RBTN2, RBTNL1, Rhom-2, RHOM2, rhombotin-2, Ttg2, TTG2, wu:fc83a08, xlmo2, zgc:111930

Bezeichner auf Proteinebene für LMO2

  • Rhombotin-2
  • LIM domain only 2 (rhombotin-like 1)
  • LIM domain only protein 2
  • LIM only 2
  • LMO-2
  • T-cell translocation protein 2
  • cysteine-rich protein TTG-2
  • rhombotin-2
  • T-cell translocation gene 2
  • rhombotin 2
  • rhombotin-like 1
  • LIM domain only-2
  • ttg2
  • zlmo2
  • xLMO-2
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