C5A Proteine (C5a)

Auf www.antikoerper-online.de finden Sie aktuell 19 Complement Component 5a (C5a) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen C5A Kits (96) und C5A Antikörper (50) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 165 C5A Produkte verfügbar.
Synonyme:
C5, C5A, C5AR, C5b, C5R1, CD88, CPAMD4, Hc, He, RGD1561905
alle Proteine anzeigen Gen GeneID UniProt
C5a 362119  
C5a 727 P01031
C5a 15139 P06684

C5A Proteine (C5a) nach Spezies

Weitere Proteine zu C5A Interaktionspartnern

Human Complement Component 5a (C5a) Interaktionspartner

  1. data indicate that properdin enhances platelet/granulocyte aggregates (PGAs) formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation

  2. Increased C5a expression is associated with increased inflammation in cystic fibrosis (zeige S100A8 Proteine).

  3. Results showed that 7-oxygenated cholesterol derivatives have differential effects on monocyte/macrophage expression of IL-8 (zeige IL8 Proteine) and C5a receptor and that C5a receptor is involved in 7alphaOHChol-induced IL-8 (zeige IL8 Proteine) expression via PI3K (zeige PIK3CA Proteine) and MEK (zeige MAP2K1 Proteine). Study demonstrated expression of IL-8 (zeige IL8 Proteine) and C5a receptor primarily by 7alpha-hydroxycholesterol in monocytes/macrophages.

  4. Reducing RPS19 (zeige RPS19 Proteine) in tumor cells or blocking the C5a receptor 1-RPS19 (zeige RPS19 Proteine) interaction decreases RPS19 (zeige RPS19 Proteine)-mediated immunosuppression, impairs tumor growth, and delays the development of tumors in a transgenic model of breast cancer

  5. C5aR (zeige C5AR1 Proteine) expression in gastric cancer was associated with cancer progression, liver metastasis, and poor prognosis.

  6. this study shows that downregulation of CD88 (zeige C5AR1 Proteine) after stimulation with IL-8 (zeige IL8 Proteine) is more pronounced in adults than in neonates, whereas fMLP (zeige FPR1 Proteine) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults

  7. Relation of C5aR (zeige C5AR1 Proteine) expression to tumor development and poor prognosis of the breast cancer patients

  8. In an arterial thrombosis model, plasminogen activator administration increased C5a levels. Overall, these findings suggest plasmin bridges thrombosis and the immune response by liberating C5a and inducing MAC assembly.

  9. The objective of the present study was to validate a receptor occupancy (RO) assay for a human anti-C5aR (zeige C5AR1 Proteine) monoclonal antibody drug candidate, NNC0215-0384 (NN0384)

  10. These data thus suggest that C5aR1 acts as an enhancer of CCR5-mediated HIV entry into macrophages, the targeting of which may prove useful to reduce HIV infection by R5 strains.

Mouse (Murine) Complement Component 5a (C5a) Interaktionspartner

  1. n the complex but clinically relevant DH model the local and systemic inflammatory immune response features both, C5-dependent and C5-independent characteristics. Activation of caspase-3 (zeige CASP3 Proteine) in lung tissue after DH was C5-dependent whereas local inflammation in lung tissue was C5-independent.

  2. The C5a/C5aR pathway is essential for up-regulating SphK1 (zeige SPHK1 Proteine) expression through p38 MAPK (zeige MAPK14 Proteine) activation in acute liver failure.in mice.

  3. We induced anti-myeloperoxidase (zeige MPO Proteine) vasculitis in bone marrow chimaeric mice and found that circulating and not bone marrow-derived C5 was required for disease

  4. Choroidal neovascularization lesions trigger a systemic immune response, augmenting local ocular inflammation via the infiltration of IL-17 (zeige IL17A Proteine)-producing gamma-delta T-cells, which are presumably recruited to the eye in a C5a-dependent manner.

  5. Data (including data from studies in knockout mice) suggest that C5aR/C5aR (zeige C5AR1 Proteine) (complement C5a/anaphylatoxin (zeige C5 Proteine) C5a Receptor) signaling pathway is involved in neurocognitive injury in uninfected pups induced by malaria in pregnancy.

  6. Carboxypeptidase B2 (zeige CPB2 Proteine) deficiency reveals that complement C5a exacerbates infection in a murine polymicrobial sepsis model.

  7. our results suggest that the detrimental effects of C5a in this model are partly mediated through CCR5 activation downstream of C5aR1 (zeige C5AR1 Proteine), which may be evaluated for potential therapeutic exploitation in ALI/ARDS.

  8. C5a signaling increases the expression of the chemokine (zeige CCL1 Proteine) monocyte chemoattractant protein-1 (zeige CCL2 Proteine) in hepatic metastases of colon cancer

  9. Properdin (zeige CFB Proteine) provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6 (zeige IL6 Proteine)-dependent manner.

  10. C5a produced during lung injury binds to C5aR (zeige C5AR1 Proteine) in alveolar macrophages, initiates downstream signaling that promotes autophagy.

C5A (C5a) Protein Überblick

Protein Überblick

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Alternative names and synonyms associated with C5A (C5a)

  • complement component 5 (C5)
  • complement component 5a receptor 1 (C5AR1)
  • hemolytic complement (Hc)
  • C5 Protein
  • C5A Protein
  • C5AR Protein
  • C5b Protein
  • C5R1 Protein
  • CD88 Protein
  • CPAMD4 Protein
  • Hc Protein
  • He Protein
  • RGD1561905 Protein

Bezeichner auf Proteinebene für Complement Component 5a Proteine (C5a)

anaphylatoxin , complement C5 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 , C5a anaphylatoxin , anaphylatoxin C5a analog , prepro-C5 , C5a anaphylatoxin chemotactic receptor 1 , C5a anaphylatoxin receptor , C5a ligand , C5a-R , complement component 5 receptor 1

GENE ID SPEZIES
362119 Rattus norvegicus
727 Homo sapiens
728 Homo sapiens
15139 Mus musculus
Ausgewählte Anbieter für C5A Proteine (C5a)
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