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IL-11 ELISA Kit (Interleukin 11) ELISA Kit

IL11 Reaktivität: Human Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum
Produktnummer ABIN6719750
$529.00
Zzgl. Versandkosten $45.00
1 kit
Lieferung in 1 bis 2 Werktagen
  • Target Alle IL-11 (IL11) ELISA Kits anzeigen
    IL-11 (IL11)
    Reaktivität
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Detektionsbereich
    31.2 pg/mL - 2000 pg/mL
    Untere Nachweisgrenze
    31.2 pg/mL
    Applikation
    ELISA
    Verwendungszweck
    Sandwich ELISA for Quantitative Detection of Antigen
    Proben
    Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum
    Analytische Methode
    Quantitative
    Produktmerkmale

    Synonyms: Adipogenesis inhibitory factor, AGIF, IL 11, IL-11, Il11, IL11_HUMAN, Interleukin 11, Interleukin-11, Interleukin11, Oprelvekin

    Background: Interleukin 11(IL-11) is a protein that in humans is encoded by the IL11 gene. The protein encoded by this gene is a member of the gp130 family of cytokines. This gene is mapped to 19q13.42. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. What's more, IL-11 can stimulate the growth of certain lymphocytes and it has functions in many other tissues, including the brain, gut, testis and bone. In transgenic mice, overexpression of the human IL11 gene resulted in the stimulation of bone formation to increase cortical thickness and strength of long bones.

    Gene Name: IL11

    Production: Natural and recombinant human IL-11. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: E.coli, Immunogen sequence: P22-L199

  • Applikationshinweise

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human IL-11 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernatants, serum or plasma(heparin, EDTA, citrate) to each empty well. We recommend that each human IL-11 standard solution and each sample is measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 31.2pg/mL-2000pg/mL

    Other Performance Data: DOE: 2-8° C- 02/30/19 -20° C - 08/30/19

    Probenmenge
    100 μL
    Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Target Alle IL-11 (IL11) ELISA Kits anzeigen
    IL-11 (IL11)
    Andere Bezeichnung
    IL-11 (IL11 Produkte)
    Synonyme
    IL11, AGIF, IL-11, Il-11, interleukin 11, IL11, Il11
    Gen-ID
    3589
    NCBI Accession
    NP_000632
    UniProt
    P20809
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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