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IL-24 ELISA Kit

IL24 Reaktivität: Maus AA 27-181 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
Produktnummer ABIN5692204
  • Target Alle IL-24 (IL24) ELISA Kits anzeigen
    IL-24 (IL24) (Interleukin 24 (IL24))
    Bindungsspezifität
    AA 27-181
    Reaktivität
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Detektionsbereich
    62.5 pg/mL - 4000 pg/mL
    Untere Nachweisgrenze
    62.5 pg/mL
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse IL-24. 96wells/kit, with removable strips.
    Marke
    PicoKine™
    Proben
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytische Methode
    Quantitative
    Spezifität
    Expression system for standard: E.coli, Immunogen sequence: Q27-L181
    Sensitivität
    < 10 pg/mL
    Bestandteile
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
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  • Testdauer
    0.5 h
    Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle IL-24 (IL24) ELISA Kits anzeigen
    IL-24 (IL24) (Interleukin 24 (IL24))
    Andere Bezeichnung
    Il24 (IL24 Produkte)
    Synonyme
    C49A ELISA Kit, FISP ELISA Kit, IL10B ELISA Kit, MDA7 ELISA Kit, MOB5 ELISA Kit, ST16 ELISA Kit, Mda7 ELISA Kit, St16 ELISA Kit, Mda-7 ELISA Kit, IL24 ELISA Kit, interleukin 24 ELISA Kit, IL24 ELISA Kit, Il24 ELISA Kit
    Hintergrund

    Synonyms: Interleukin-24, IL-24, Melanoma differentiation-associated gene 7 protein, MDA-7, Suppression of tumorigenicity 16 protein, IL24, MDA7, ST16

    Tissue Specificity: Up-regulated in melanoma cells induced to terminally differentiate.

    Background: Interleukin 24 (IL-24) is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as Melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. By radiation hybrid analysis, the MDA7 gene is mapped to 1q32.2-q41. IL-24 appears to control in cell survival and proliferation by inducing rapid activation of particular transcription factors called Stat-1 and Stat-3. Mouse IL24 was expressed as an approximately 35-kD protein that was converted to a 23-kD protein by deglycosylation. The IL24 protein shares 24 to 33 % homology with other members of the IL10 family of cytokines, with highest homology with IL20. This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer.

    Cellular Localisation: Secreted.
    UniProt
    Q13007
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie
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