CFP ELISA Kit

Produktnummer ABIN5692201

Produktdetails CFP ELISA Kit

Target: CFP (Complement Factor P (CFP))

Bindungsspezifität: AA 28-469

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 312 pg/mL - 20000 pg/mL

Untere Nachweisgrenze: 312 pg/mL

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Properdin. 96wells/kit, with removable strips.

Marke: PicoKine™

Proben: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO, Immunogen sequence: D28-L469

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover

Anwendungsinformationen

Testdauer: 0.5 h

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu CFP

Target: CFP (Complement Factor P (CFP))

Andere Bezeichnung: CFP (CFP Produkte)

Synonyme: BFD ELISA Kit, PFC ELISA Kit, PFD ELISA Kit, PROPERDIN ELISA Kit, BCFG ELISA Kit, Pfc ELISA Kit, Properdin ELISA Kit, complement factor properdin ELISA Kit, CFP ELISA Kit, Cfp ELISA Kit

Hintergrund:

Synonyms: Properdin, Complement factor P, CFP, PFC

Background: Properdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localisation: Secreted.

UniProt: P27918

Pathways: Komplementsystem