Sclerostin ELISA Kit

Produktnummer ABIN5510722

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Ratte Sclerostin.

Kurzübersicht für Sclerostin ELISA Kit (ABIN5510722)

Target: Sclerostin (SOST)

Bindungsspezifität: AA 29-213

Reaktivität: Ratte

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails Sclerostin ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Sclerostin/SOST

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: F29-Y213

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu Sclerostin

Target: Sclerostin (SOST)

Andere Bezeichnung: Sost

Hintergrund:

Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .

Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.

Synonyms: Sclerostin,Sost,

Full Gene Name: Sclerostin

Cellular Localisation: Secreted.

UniProt: Q99P67