Syndecan 1 ELISA Kit

Produktnummer ABIN5510712

Maus Syndecan 1 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Maus Syndecan 1.

Kurzübersicht für Syndecan 1 ELISA Kit (ABIN5510712)

Target: Syndecan 1 (SDC1)

Bindungsspezifität: AA 18-252

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails Syndecan 1 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Syndecan-1/SDC1

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: Q18-E252

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: Sdc1

Hintergrund:

Protein Function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. .

Background: Syndecan 1, also known as SYND1 or CD138, is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. This gene is mapped to 2p24.1. The syndecans mediate cell binding, cell signaling, cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan 1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. What’s more, Syndecan-1 is also a sponge for growth factors, with binding largely via heparan sulfate chains.

Synonyms: Syndecan-1,SYND1,CD138,Sdc1,Synd-1, Synd1,

Full Gene Name: Syndecan-1

Cellular Localisation: Membrane, Single-pass type I membrane protein . Secreted . Secreted, exosome . Shedding of the ectodomain produces a soluble form..

UniProt: P18828

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism