KREMEN1 ELISA Kit

Produktnummer ABIN5510702

Dieses Maus KREMEN1 ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Maus KREMEN1 zu quantifizieren.

Kurzübersicht für KREMEN1 ELISA Kit (ABIN5510702)

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Bindungsspezifität: AA 20-395

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails KREMEN1 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Kremen-1

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: A20-G395

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu KREMEN1

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Andere Bezeichnung: Kremen1

Hintergrund:

Protein Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). .

Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Synonyms: Kremen protein 1,Dickkopf receptor,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,Kremen1,Kremen,

Full Gene Name: Kremen protein 1

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q99N43

Pathways: WNT Signalweg