SFRP5 ELISA Kit

Produktnummer ABIN5510650

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Human SFRP5.

Kurzübersicht für SFRP5 ELISA Kit (ABIN5510650)

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Bindungsspezifität: AA 30-317

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails SFRP5 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human SFRP5

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: CHO
Immunogen sequence: E30-H317

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu SFRP5

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Andere Bezeichnung: SFRP5

Hintergrund:

Protein Function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.

Background: Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene. SFRP5 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.

Synonyms: Secreted frizzled-related protein 5,sFRP-5,Frizzled-related protein 1b,FRP-1b,Secreted apoptosis-related protein 3,SARP-3,SFRP5,FRP1B, SARP3,

Full Gene Name: Secreted frizzled-related protein 5

Cellular Localisation: Secreted.

UniProt: Q5T4F7

Pathways: WNT Signalweg