IL-10 ELISA Kit
Kurzübersicht für IL-10 ELISA Kit (ABIN5068378)
Target
Alle IL-10 (IL10) ELISA Kits anzeigenReaktivität
Nachweismethode
Methodentyp
Applikation
Proben
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Kreuzreaktivität (Details)
- Calculated cross reactivity: Hu
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Sensitivität
- 3.5 pg/mL
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Produktmerkmale
- Interleukin 10, Human, Low Range (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF) ELISA Kit
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Bestandteile
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- Microtiter Plate 1x96 wells
- Pab (Biotin) 1x7ml
- Avidin (HRP) 1x14ml
- * Standard 2x1vial
- Calibrator Diluent I 1x22ml
- Calibrator Diluent II (5X) 1x22ml
- Wash Buffer (20X) 1x60ml
- Substrate A 1x10ml
- Substrate B 1x10ml
- Stop Solution 1x14ml
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C/-20°C
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- IL-10 (IL10) (Interleukin 10 (IL10))
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Andere Bezeichnung
- Interleukin 10
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Hintergrund
- Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of murine TH2 clones that suppressed the production of cytokines by TH1 clones responding to stimulation by antigen in the presence of monocyte/macrophage antigen-presenting cells. The human homolog of murine IL-10 was subsequently cloned by cross-hybridization. Human and murine IL-10 are 81 % and 73 % identical at the nucleotide and amino acid levels, respectively. Both mouse and human IL-10 are also highly homologous to a previously uncharacterized open reading frame in the Epstein-Barr virus (EBV) genome, BCRF1. The BCRF1 gene product is now designated viral IL-10. In mouse, IL-10 is produced by TH2 cells, activated fetal thymocytes, macrophages, keratinocytes, and LY-1+ (CD5+) and normal B cells. Cell lines found to have the capacity to produce IL-10 in humans include: TH0, TH1, and TH2-like CD4+ T cell clones, B cell lines derived from patients with AIDS and Burkitt's lymphoma, activated monocytes and peripheral blood T cells, including TH2-like CD8, CD4+CD45RA naive and CD4+CD45RA memory T cells, plus bronchogenic carcinoma cells.
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Target Alle IL-10 (IL10) ELISA Kits anzeigen
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