PD-L1 ELISA Kit

Produktnummer ABIN4993798

Dieses Colorimetric ELISA kit dient der quantitativen Messung von Human PD-L1.

Kurzübersicht für PD-L1 ELISA Kit (ABIN4993798)

Target: PD-L1 (CD274 (PD-L1))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 5.58-15000 pg/mL

Applikation: ELISA

Proben: Cell Culture Supernatant, Plasma, Serum

Produktdetails PD-L1 ELISA Kit

Untere Nachweisgrenze: 5.58 pg/mL

Verwendungszweck: This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human B7-H1.

Analytische Methode: Quantitative

Spezifität: B7H1

Bestandteile: plate, standard, diluent

Benötigtes Material: pipettes, tubes, reader

Anwendungsinformationen

Probenmenge: 100 μL

Testdauer: 3 - 4 h

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu PD-L1

Target: PD-L1 (CD274 (PD-L1))

Andere Bezeichnung: B7H1

Hintergrund: B7 homolog 1 (B7-H1), also known as programmed death-ligand 1 (PD-L1) and cluster of differentiation 274 (CD274), is a 40 kDa type I transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. The binding of B7-H1 to its receptor transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes.

NCBI Accession: NM_021893

UniProt: Q9EP73

Pathways: Cancer Immune Checkpoints