Interferon gamma ELISA Kit

Produktnummer ABIN2690557

Human Interferon gamma ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human Interferon gamma und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für Interferon gamma ELISA Kit (ABIN2690557)

Target: Interferon gamma (IFNG)

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Proben: Serum, Plasma, Cell Culture Supernatant

Produktdetails Interferon gamma ELISA Kit

Untere Nachweisgrenze: 1.0 pg/mL

Verwendungszweck: The Human IFN-γ ELISA Kit II is for the in vitro quantitative determination of human IFN-γ in serum, plasma, and cell culture supernatant.

Marke: BD OptEIA™

Analytische Methode: Quantitative

Anwendungsinformationen

Applikationshinweise: The ELISA Kit II format was developed for superior accuracy with serum and plasma specimens. The data that demonstrates this enhancement can be located in the Performance "Recovery" and "Linearity" sections.

Kommentare:

BD OptEIA™ Human IFN-γ ELISA Kit II

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Informationen zur Lagerung: 1. Store unopened kit at 2 - 8°C. Do not use kit after expiration date.
2. Before use, bring all reagents to room temperature (18 - 25°C). Immediately after use, return to proper storage conditions.
3. Lyophilized standards are stable until kit expiration date. After reconstitution, use freshly reconstituted standard within 12 hours (stored at 2 - 8°C).

Referenzen für Interferon gamma ELISA Kit (ABIN2690557)

Farrar, Schreiber: "The molecular cell biology of interferon-gamma and its receptor." in: Annual review of immunology, Vol. 11, pp. 571-611, (1993) (PubMed).

Grossberg, Taylor, Kushnaryov: "Interferon receptors and their role in interferon action." in: Experientia, Vol. 45, Issue 6, pp. 508-13, (1989) (PubMed).

Zoon: "Human interferons: structure and function." in: Interferon, Vol. 9, pp. 1-12, (1988) (PubMed).

Rinderknecht, OConnor, Rodriguez: "Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation." in: The Journal of biological chemistry, Vol. 259, Issue 11, pp. 6790-7, (1984) (PubMed).

DeGrado, Wasserman, Chowdhry: "Sequence and structural homologies among type I and type II interferons." in: Nature, Vol. 300, Issue 5890, pp. 379-81, (1983) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFN-gamma

Hintergrund: Interferon-γ (IFN-γ) or immune interferon, is a potent multifunctional Type II interferon which is secreted by activated natural killer (NK) cells and T cells. IFN-γ binds to a different receptor than the Type I viral interferons IFN-α and IFN-β, with which little sequence homology is shared.
In addition to its antiviral effects, IFN-γ can upregulate a number of lymphoid cell functions, including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN-γ can exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. These influences can involve IFN-γ's capacity to boost MHC class I and II expression by antigen-presenting cells as well as direct effects on B cells and T cells themselves. Human IFN-γ is a 35 kD protein containing 143 amino acid residues. This cytokine also upregulates ICAM-1 expression on endothelial cells, and has become a primary marker for Th1-like immune response research.

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie