CXCL2 ELISA Kit

Produktnummer ABIN2648786

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Ratte CXCL2.

Kurzübersicht für CXCL2 ELISA Kit (ABIN2648786)

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reaktivität: Ratte

Nachweismethode: Colorimetric

Applikation: ELISA

Proben: Serum, Plasma, Cell Culture Cells

Produktdetails CXCL2 ELISA Kit

Verwendungszweck: Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit (enzyme-linked immunoassay kit) is intended for the quantitative determination of rat macrophage inflammatory protein-2 (MIP-2 ) concentrations in cell culture supernates, serum, and plasma.

Analytische Methode: Quantitative

Produktmerkmale: Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit is for research use only and not to be used in diagnostic procedures.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Testdauer: 3.5 h

Plattentyp: Pre-coated

Protokoll: Macrophage inflammatory protein-2(MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The protein is produced by a variety of cell types, including intestinal epithelium, macrophages, astrocytes and fibroblasts. Homologs of the mouse MIP-2 have been identified in human, rat and cotton rat. MIP-2 is an ELR-containing member of the alpha (CXC) subfamily of chemokines. The cotton rat MIP-2 gene encodes a 101 amino acid (aa) residue precursor protein with a 28 aa putative signal peptide that is cleaved to generate the 73 aa mature protein. Mature cotton rat MIP-2 has two intrachain disulfide bonds and no potential glycosylation sites. It shares approximately 79 % and 85 % aa sequence identity with rat CINC-3 and mouse MIP-2, respectively. MIP-2 is a potent neutrophil attractant and activator. MIP-2 binds and activates the chemokine receptor CXCR-2. The recombinant cotton rat MIP-2 has been shown to bind and activate the human CXCR-2.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Details zu CXCL2

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Andere Bezeichnung: MIP-2

Pathways: Cellular Response to Molecule of Bacterial Origin