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PLAU ELISA Kit

Dieses Human PLAU ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human PLAU zu quantifizieren.
Produktnummer ABIN2042715

Kurzübersicht für PLAU ELISA Kit (ABIN2042715)

Target

Alle PLAU ELISA Kits anzeigen
PLAU (Plasminogen Activator, Urokinase (PLAU))

Reaktivität

  • 12
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Nachweismethode

Colorimetric

Methodentyp

Sandwich ELISA

Detektionsbereich

62.5-4000 pg/mL

Applikation

ELISA
  • Untere Nachweisgrenze

    62.5 pg/mL

    Kreuzreaktivität (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivität

    < 5 pg/mL

    Bestandteile

    96-well plate pre-coated with anti-uPA/PLAU, Human
    Lyophilized recombinant uPA/PLAU, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plattentyp

    Pre-coated

    Protokoll

    Sandwich ELISA quantitative detection kit for Human uPA/PLAU in cell culture supernates, serum and plasma (heparin, EDTA).Plasminogen activator,urokinase (PLAU, uPA) converts plasminogen to plasmin. Plasmin is involved in processing of amyloid precursor protein and degrades secreted and aggregated amyloid-beta, a hallmark of Alzheimer disease (AD). Urokinase has a molecular mass of about 54kD and is composed of 2 disulfide-linked chains, A and B, of molecular masses 18kD and 33kD, respectively. It localized on 10q24. uPA facilitates cell migration by localizing proteolisys on the cell surface and by inducing intracellular signalling pathways. In human vascular smooth muscle cell (VSMC), uPA stimulates migration via the uPA receptor (uPAR) signalling complex containing TYK2 and phosphatidylinositol 3-kinase (PI3-K).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C/-20 °C
  • Target Alle PLAU ELISA Kits anzeigen

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    Andere Bezeichnung

    uPA/PLAU

    Gen-ID

    5328

    UniProt

    P00749

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration
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