Cathepsin D ELISA Kit

Produktnummer ABIN2042373

Dieses Maus Cathepsin D ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Maus Cathepsin D zu quantifizieren.

Kurzübersicht für Cathepsin D ELISA Kit (ABIN2042373)

Target: Cathepsin D (CTSD)

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 6-10000 pg/mL

Applikation: ELISA

Produktdetails Cathepsin D ELISA Kit

Untere Nachweisgrenze: 6 pg/mL

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate pre-coated with anti-Cathepsin D, Mouse
Lyophilized recombinant Cathepsin D, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Mouse Cathepsin D in cell culture supernates, serum and plasma (heparin, EDTA).Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: Cathepsin D

Gen-ID: 13033

UniProt: P18242

Pathways: Peptide Hormone Metabolism