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KIR3DL2 Proteine

(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011].

6 Treffer

KIR3DL2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275102
 
KIR3DL2 Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275101
 
KIR3DL2 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS
Produktnummer ABIN6388088
 
KIR3DL2 Spezies: Human Wirt: Mammalian Cells Recombinant SDS, WB, ELISA
Produktnummer ABIN7575531
 
KIR3DL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7403849
 
KIR3DL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3010365
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Immunoprecipitation (IP)
    • Positive Control (PC)
  • Reaktivität
    • Human
    • Rhesus Monkey
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Baculovirus infected Insect Cells
    • Mammalian Cells
  • Bindungsspezifität
    • AA 184-435
    • AA 22-338
    • AA 22-339
    • AA 22-340
  • Konjugat
    • Fc Tag
    • His tag
    • His tag,GST tag
    • His-Avi Tag
    • hIgG-His-tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • Abbexa

Aliase für KIR3DL2 Proteine

killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 (KIR3DL2) Proteine
CD158K Proteine
NKAT-4 Proteine
NKAT4 Proteine
NKAT4B Proteine
p140 Proteine
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