KCNJ3 Produkte
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))
Kategorien
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012].
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Ausgewählte KCNJ3 Kategorien
KCNJ3 Antikörper
High quality antibodies with extensive validation data.
KCNJ3 ELISA Kits
Reliable ELISA kits for a wide range of species.
KCNJ3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KCNJ3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Monkey, Mouse
Applikation
WB, IF, IHC, FACS, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1491310
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN719741
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, IHC, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6262821
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene KCNJ3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380445
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene KCNJ3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3082233
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3120859
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3113708
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KCNJ3 Produkten
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).: "A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1765-73, (2014) (PubMed).
Synonyme und alternative Namen zu KCNJ3
potassium voltage-gated channel subfamily J member 3 (KCNJ3), potassium inwardly-rectifying channel, subfamily J, member 3 (Kcnj3), potassium voltage-gated channel subfamily J member 3 (Kcnj3), GIRK1, girk1, Kcnf3, KGA, KIR3.1, Kir3.1Bezeichner auf Proteinebene für KCNJ3
- G protein-activated inward rectifier potassium channel 1
- GIRK-1
- inward rectifier K(+) channel Kir3.1
- inward rectifier K+ channel KIR3.1
- potassium channel, inwardly rectifying subfamily J member 3
- potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e
- potassium inwardly-rectifying channel J3
- GIRK1
- KGA
- KGB1
- potassium channel inwarding rectifying channel subfamily J member 3
- potassium channel subunit Kir3.1 type 3 delta
- inward rectifying potassium channel, Kir3.1
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