KCNJ3 Antikörper (Internal Region)
Kurzübersicht für KCNJ3 Antikörper (Internal Region) (ABIN6262821)
Target
Alle KCNJ3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- GIRK1/KIR3.1/KCNJ3 Antibody detects endogenous levels of total GIRK1/KIR3.1/KCNJ3.
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Homologie
- Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))
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Andere Bezeichnung
- KCNJ3
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Hintergrund
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Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Gene: KCNJ3
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Molekulargewicht
- 43kDa
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Gen-ID
- 3760
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UniProt
- P48549
Target
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