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KAT2A Produkte

(K(lysine) Acetyltransferase 2A (KAT2A))

Kategorien

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009].

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Ausgewählte KAT2A Kategorien

KAT2A Antikörper

High quality antibodies with extensive validation data.

KAT2A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KAT2A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN7260323
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (8)
Kat. Nr. ABIN1679964
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (3)
Kat. Nr. ABIN515990
Menge 100 μg
Datenblatt Datenblatt

Empfohlene KAT2A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123656
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308356
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308354
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KAT2A Produkten

Zhang, Li, Rezaeian, Xu, Chou, Jin, Han, Pan, Wang, Long, Zhang, Huang, Tsai, Tsai, Logothetis, Lin: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).

Hu, Liu, Zhang, Xu, Ma, Chen, Wang, He, Zhu, Xu: "Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay." in: Molecular carcinogenesis, Vol. 54, Issue 10, pp. 1051-9, (2015) (PubMed).

Smith, Syed, Lukacsovich, Purcell, Barbaro, Worthge, Wei, Pollio, Magnoni, Scali, Massai, Franceschini, Camarri, Gianfriddo, Diodato, Thomas, Gokce, Tabrizi, Caricasole, Landwehrmeyer, Menalled et al.: "A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. ..." in: Human molecular genetics, Vol. 23, Issue 11, pp. 2995-3007, (2014) (PubMed).

Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

Wiper-Bergeron, Salem, Tomlinson, Wu, Haché: "Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2703-8, (2007) (PubMed).

Oishi, Kitagawa, Wada, Takezawa, Tora, Kouzu-Fujita, Takada, Yano, Yanagisawa, Kato: "An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification." in: The Journal of biological chemistry, Vol. 281, Issue 1, pp. 20-6, (2006) (PubMed).

Kikuchi, Takami, Nakayama: "GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes." in: Gene, Vol. 347, Issue 1, pp. 83-97, (2005) (PubMed).

Gangisetty, Lauffart, Sondarva, Chelsea, Still: "The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases." in: Oncogene, Vol. 23, Issue 14, pp. 2559-63, (2004) (PubMed).

Lusic, Marcello, Cereseto, Giacca: "Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter." in: The EMBO journal, Vol. 22, Issue 24, pp. 6550-61, (2003) (PubMed).

Brand, Moggs, Oulad-Abdelghani, Lejeune, Dilworth, Stevenin, Almouzni, Tora: "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation." in: The EMBO journal, Vol. 20, Issue 12, pp. 3187-96, (2001) (PubMed).

Synonyme und alternative Namen zu KAT2A

K(lysine) acetyltransferase 2A (KAT2A), lysine acetyltransferase 2A (KAT2A), histone acetyltransferase KAT2A (LOC100176452), ras-related protein Rab-5C (LOC100597293), K(lysine) acetyltransferase 2A (Kat2a), lysine acetyltransferase 2A (Kat2a), 1110051E14Rik, AW212720, GCN5, Gcn5, GCN5L2, Gcn5l2, hGCN5, KAT2A, mmGCN5, PCAF-b

Bezeichner auf Proteinebene für KAT2A

  • histone acetyltransferase KAT2A
  • general control of amino acid synthesis 5-like 2
  • GCN5 general control of amino-acid synthesis 5-like 2
  • general control of amino acid synthesis protein 5-like 2
  • K(lysine) acetyltransferase 2A
  • GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
  • General control of amino acid synthesis, yeast, homolog-like 2
  • STAF97
  • histone acetyltransferase GCN5
  • hsGCN5
  • lysine acetyltransferase 2A
  • GCN5 general control of amino acid synthesis-like 2
  • PCAF-B/GCN5
  • general control of amino acid synthesis, yeast homolog-like 2
  • general control of amino acid synthesis-like 2
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