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KARS Produkte

(Lysyl-tRNA Synthetase (KARS))
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte KARS Kategorien

KARS Antikörper

High quality antibodies with extensive validation data.

KARS ELISA Kits

Reliable ELISA kits for a wide range of species.

KARS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KARS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN7268350
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (4)
  • (3)
Kat. Nr. ABIN969226
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ICC, IHC (p), IF
Validierungen
  • (4)
Kat. Nr. ABIN2855293
Menge 100 μL
Datenblatt Datenblatt

Empfohlene KARS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957609
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957610
Menge 96 tests
Datenblatt Datenblatt

Empfohlene KARS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308352
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123818
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
Kat. Nr. ABIN3128062
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KARS Produkten

Guo, Ignatov, Musier-Forsyth, Schimmel, Yang: "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2331-6, (2008) (PubMed).

Kaminska, Francin, Shalak, Mirande: "Role of HIV-1 Vpr-induced apoptosis on the release of mitochondrial lysyl-tRNA synthetase." in: FEBS letters, Vol. 581, Issue 16, pp. 3105-10, (2007) (PubMed).

Kovaleski, Kennedy, Khorchid, Kleiman, Matsuo, Musier-Forsyth: "Critical role of helix 4 of HIV-1 capsid C-terminal domain in interactions with human lysyl-tRNA synthetase." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32274-9, (2007) (PubMed).

Sampath, Mazumder, Seshadri, Gerber, Chavatte, Kinter, Ting, Dignam, Kim, Driscoll, Fox: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." in: Cell, Vol. 119, Issue 2, pp. 195-208, (2004) (PubMed).

Sang Lee, Gyu Park, Park, Seol, Lee, Kim: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." in: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, (2002) (PubMed).

Cen, Khorchid, Javanbakht, Gabor, Stello, Shiba, Musier-Forsyth, Kleiman: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." in: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, (2001) (PubMed).

Tolkunova, Park, Xia, King, Davidson: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, (2000) (PubMed).

Synonyme und alternative Namen zu KARS

Lysyl-tRNA synthetase (LysRS), lysyl-tRNA synthetase (kars), lysyl-tRNA synthetase S homeolog (kars.S), lysyl-tRNA synthetase L homeolog (kars.L), lysyl-tRNA synthetase (Bm1_16500), lysyl-tRNA synthetase (lysS), Lysyl-tRNA synthetase (lysS), lysyl-tRNA synthetase (Taci_1118), lysyl-tRNA synthetase (Tpau_1737), lysyl-tRNA synthetase (Arch_0261), lysyl-tRNA synthetase (Trad_2960), lysyl-tRNA synthetase (Spirs_3699), lysyl-tRNA synthetase (KARS), lysyl-tRNA synthetase (LOC100280510), lysyl-tRNA synthetase (Tb927.6.1510), lysyl-tRNA synthetase (Kars), AA589550, AL024334, AL033315, AL033367, cb530, CG12141, CMTRIB, D8Ertd698e, D8Wsu108e, DFNB89, Dmel\\CG12141, kars, KARS, KARS1, kars2, KARS2, KRS, krs, krs-1, LysRS, MGC53345, mKIAA0070, Tb06.28P18.190, wu:fa16h02, zgc:92483

Bezeichner auf Proteinebene für KARS

  • Aats-lys-PA
  • Aats-lys-PB
  • Aats-lys-PC
  • CG12141-PA
  • CG12141-PB
  • CG12141-PC
  • fa16h02
  • lysine--tRNA ligase
  • lysyl-tRNA synthetase
  • lysRS
  • lysine tRNA ligase
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